
A proteomic landscape of diffuse-type gastric cancer - PubMed
2018年3月8日 · The diffuse-type gastric cancer (DGC) is a subtype of gastric cancer with the worst prognosis and few treatment options. Here we present a dataset from 84 DGC patients, …
天然 DGC 结构使导致肌营养不良的突变合理化,Nature - X-MOL
杜氏肌营养不良症 (DMD) 是一种严重的 X 连锁隐性遗传病,其特征是进行性肌肉萎缩,导致过早死亡 1,2。 编码抗肌萎缩蛋白的 DMD 基因的发现既揭示了 DMD 的原因,又有助于在肌肉 …
《科学》子刊:兰大科学家找到弥漫性胃癌的新突破点!
2022年7月1日 · 该团队在人源化nsg小鼠中建立了dgc pdx模型,从dgc患者中获得新鲜肿瘤标本,并连续移植到nsg小鼠中以产生足够数量的原发肿瘤组织。
天然DGC结构揭示肌营养不良致病突变机制 - 科学网
2024年12月13日 · Title: Native DGC structure rationalizes muscular dystrophy-causing mutations. Author: Liu, Shiheng, Su, Tiantian, Xia, Xian, Zhou, Z. Hong. Issue&Volume: 2024-12-11. …
Increasing LRP4 diminishes neuromuscular deficits in a mouse …
2021年9月9日 · Increasing genetic evidence showed that DGC is important for NMJ development and maintenance (24,54–57). Our present study showed that LRP4 increases the expression …
Native DGC structure rationalizes muscular dystrophy-causing …
2024年12月12日 · Here we determined the native cryo-electron microscopy structure of rabbit DGC and conducted biochemical analyses to reveal its intricate molecular configuration. An …
Structure and assembly of the dystrophin glycoprotein …
2024年12月12日 · 抗肌萎缩蛋白糖蛋白复合物 (DGC) 通过将细胞内细胞骨架与周围的细胞外基质连接起来,在维持细胞膜稳定性和完整性方面起着至关重要的作用 1,2,3。 抗肌萎缩蛋白及 …
A proteomic landscape of diffuse-type gastric cancer. - eScholarship
The diffuse-type gastric cancer (DGC) is a subtype of gastric cancer with the worst prognosis and few treatment options. Here we present a dataset from 84 DGC patients, composed of a …
Associate Professor | 上海交通大学设计学院 - SJTU
Dr. Lai currently works at Department of Architecture in Shanghai Jiao Tong University as an Associate Professor and Associate Head. He earned his Ph.D. degree from Purdue at 2017, …
Abstract 2204: A proteomic landscape of diffuse-type gastric cancer
2017年7月1日 · Gastric cancer is a heterogeneous disease characterized by poor clinical outcomes and limited targeted treatment options. Among them, diffuse-type gastric cancer …
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