2024年12月24日 · DNM2 (Dynamin 2) is a Protein Coding gene. Diseases associated with DNM2 include Myopathy, Centronuclear, 1 and Charcot-Marie-Tooth Disease, Dominant Intermediate …

Dynamin-2 is a protein that in humans is encoded by the DNM2 gene. [5][6] Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence …

The DNM2 gene provides instructions for making a protein called dynamin 2. Dynamin 2 is present in cells throughout the body. It is involved in endocytosis, which is a process that …

2022年11月11日 · Dynamin 2 mechanoenzyme is a key regulator of membrane remodeling and gain-of-function mutations in its gene cause centronuclear myopathies. Here, we investigate …

During the last two decades, DNM2 involvement, through mutations or overexpression, emerged in an increasing number of cancers and often associated with poor prognosis. A wide panel of …

DNM2 is a ubiquitously expressed large GTPase involved in clathrin (see 118955)-dependent and -independent endocytosis and intracellular membrane trafficking. DNM2 interacts tightly with …

关于 dnm2 Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:10,718,079-10,831,903 (from NCBI) This gene has 26 transcripts (splice variants), 315 orthologues, 6 …

Dynamin 2 (DNM2) belongs to a family of large GTPases that are well known for mediating membrane fission by oligomerizing at the neck of membrane invaginations. Autosomal …

we report a novel DNM2 mutation in the Pleckstrin homology domain of DNM2 (p.K559del) in a patient with an axonal length-dependent sensorimotor polyneuropathy predominantly affecting …

2024年2月4日 · Clinical resource with information about DNM2, Autosomal dominant centronuclear myopathy, Charcot-Marie-Tooth disease dominant intermediate B, Fetal …