
Roman J. Szczęsny, PhD, DSc, Prof. of IBB PAS - Instytut Biochemii …
Our laboratory is interested in mechanisms that control the quality, quantity, and processing of RNAs that originate from expression of the mitochondrial and nuclear genomes in humans. Our main goal is to decipher molecular machinery that is responsible for RNA surveillance.
Kevin Waldron, PhD, DSc, Prof. of IBB PAS - Instytut Biochemii i ...
We uncovered a novel mechanism by which cells regulate metal selectivity, demonstrating that a pair of closely related metalloenzymes from cyanobacteria, with nearly identical metal selectivity, are loaded in vivo with different metals, from opposite ends of the Irving-Williams series.
Tamara Aleksandrzak-Piekarczyk, PhD, DSc - Instytut Biochemii i ...
In our study, we identified a metal-dependent protease as a new membrane receptor that binds to non-translationally modified bacteriocins enterocin K1 and LsbB, affecting Enterococcus faecium and Lactococcus lactis.
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Tomasz W. Turowski, PhD, DSc - Instytut Biochemii i Biofizyki Polskiej ...
We are interested in understanding how the biophysics of transcription affects gene regulation. Our goal is to apply this knowledge to problems such as SARS-CoV-2 transcription and RNA polymerase III‑related leukodystrophy, and to improve the design of synthetic genomes. We found that folding of nascent RNA affects the kinetics of RNA polymerases.
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Magdalena Kowalczyk, PhD, DSc - Instytut Biochemii i Biofizyki …
Proteomics and metabolomics of LAB strains or complex microbial ecosystems are or will be performed in the Mass Spectrometry Facility (IBB PAS). Cell cultures are also employed to study the effects of the studied LAB strains or their metabolites on the properties of living systems.