Dab2 (Disabled-2), an adaptor protein, regulates self-renewal of …
2024年5月3日 · The adaptor protein Disabled 2 (Dab2) regulates the activation and self-renewal of hair follicle stem cells via canonical Wnt pathway. Importantly, Dab2 is also involved in the …
Identification of the Lineage Markers and Inhibition of DAB2 in In ...
2020年10月1日 · After culture, the levels of the transcript and protein expression in the embryos with or without shRNA were compared by qPCR and immunostaining. The results will help to …
Disabled 2 (Dab2) Regulates Tumour Progression in Skin …
2024年11月6日 · Furthermore, qPCR analysis showed upregulation of Dab2 expression in the human skin cancer cell lines as compared to normal human skin keratinocytes. In patients, …
Rapid Downregulation of DAB2 by Toll-Like Receptor Activation ...
2019年2月27日 · DAB2 downregulation promoted a more functional and activated DC phenotype, reduced phagocytosis, and increased CD40 expression after TLR activation. Furthermore, …
Dab2 expression is differentially regulated in M1 and M2 …
Dab2 expression is differentially regulated in M1 and M2 macrophages. mRNA expression of total Dab2 and p67 and p96 Dab2 splice variants was determined by qPCR of BMDMs (A) and …
Disabled-2: a positive regulator of the early differentiation of ...
2020年6月30日 · Results from both qPCR and western blotting showed that when C2C12 cells were induced to undergo myogenic differentiation in a culture medium with a low concentration …
JCI - Disabled homolog 2 controls macrophage phenotypic polarization ...
2016年2月29日 · We show that DAB2 inhibits NF-κB–dependent transcription by binding to TRAF6 and repressing Ser536 phosphorylation in the p65 transactivation domain of NF-κB. As …
Disabled 2 (Dab2) Regulates Tumour Progression in Skin
Furthermore, qPCR analysis showed upregulation of Dab2 expression in the human skin cancer cell lines as compared to normal human skin keratinocytes. In patients, TCGA data analysis of …
Dab2 expression controls inflammatory gene expression. qPCR …
Download scientific diagram | Dab2 expression controls inflammatory gene expression. qPCR analysis of Il1b (A) or Ptgs2 (B), which encodes cyclooxygenase 2, in RAW 264.7 …
The role of disabled-2 (Dab2) in diseases - ScienceDirect
2021年2月15日 · Dab2 expression was reported to be downregulated in mouse models of Alzheimer’s disease, and overexpression of Dab2 significantly decreases amyloid plaque …