DACT2 Gene - GeneCards | DACT2 Protein | DACT2 Antibody
2024年12月24日 · DACT2 (Dishevelled Binding Antagonist Of Beta Catenin 2) is a Protein Coding gene. Diseases associated with DACT2 include Extraocular Retinoblastoma and Retinitis …
DACT2 is a functional tumor suppressor through inhibiting Wnt
2014年7月14日 · Restoring DACT2 expression in colon cancer cell lines suppressed tumor cell growth by inducing cell apoptosis and inhibiting cell proliferation both in vitro and in vivo. …
DACT2 dishevelled binding antagonist of beta catenin 2
2025年2月8日 · DACT2 suppresses hepatocellular carcinoma by inhibiting Wnt signaling in human hepatocellular carcinoma cells. Loss of DACT2 expression is associated with …
DACT2 is a functional tumor suppressor through inhibiting Wnt/β …
2015年5月5日 · Restoring DACT2 expression in colon cancer cell lines suppressed tumor cell growth by inducing cell apoptosis and inhibiting cell proliferation both in vitro and in vivo. …
Epigenetic regulation of DACT2, a key component of the Wnt
Dapper, Dishevelled-associated antagonist of β-catenin (DACT), is involved in Xenopus embryonic development. Human DACT2 is localized on chromosome 6q27, a region of …
Epigenetic regulation of DACT2, a key component of the Wnt …
To explore the function and regulation of DACT2 in lung cancer, we analysed genetic and epigenetic changes of DACT2, and determined the potential involvement of this gene as a …
DACT2 modulates atrial fibrillation through TGF/β and Wnt …
2024年8月30日 · DACT2 inhibits TGF-β and Wnt signaling pathways by suppressing the phosphorylation of β-catenin on Thr41/Ser45 in HL-1 cells, thereby attenuating the levels of …
Upregulation of DACT2 suppresses proliferation and enhances apoptosis ...
2017年8月10日 · DACT2, one of the Dact gene family members, was shown to function as a tumor suppressor. However, its function in gliomas remains largely unknown. In this study, we …
Dact2 Represses PITX2 Transcriptional Activation and Cell ... - PLOS
2013年1月22日 · Dact2 significantly inhibits PITX2 activation of the Dlx2 and amelogenin promoters. Multiple lines of evidence conclude the inhibition is achieved by the physical …
Dact2 is involved in the regulation of epithelial-mesenchymal ...
2020年3月26日 · Dact2 promotes Dishevelled degradation in the lysosome-dependent pathway and inhibits LEF1 binding to beta-catenin; re-expression of Dact2 stimulates transcriptional …