STEM careers are growing exponentially, with an estimated 8.8% predicted employment demand in the next decade, compared to 5% for non-STEM occupations (US Bureau of Lab. Stat., 2019), and...

2020年12月9日 · This study presents the methodological and procedural development process of the Digital Age Teaching Scale (DATS), a summative assessment tool designed to measure application of the ISTE ...

2022年4月1日 · Diallyl disulfide (DADS) and diallyl trisulfide (DATS) are the main allyl sulfur compounds present in garlic, and are known to exhibit anticancer activity as they interfere with breast cancer cell proliferation, tumor metastasis, and angiogenesis.

The findings demonstrate the ΔNp63/SHH pathway’s significant role in suppressing gastric cancer stem cell characteristics by DATS. DATS demonstrates therapeutic efficacy against a diverse range of tumors, encompassing triple-negative breast cancer, ovarian cancer, and …

2024年1月16日 · Overall, DATS inhibited cell proliferation; induced cell cycle mitotic arrest and apoptosis involving DNA damage through ROS generation; reduced the CSC fraction and spheroid formation; and downregulated SOX2 and Oct4 expression. More importantly, DATS inhibited HNSCC tumor growth and CSC fraction in vivo.

Diallyl trisulfide (DATS), a bioactive compound derived from Allium vegetables, has been investigated as an anti-cancer and chemopreventive agent. Preclinical studies provide ample evidence that DATS regulates multiple cancer hallmark pathways including cell cycle, apoptosis, angiogenesis, invasion, and metastasis.

2023年10月13日 · SITAR facilitated DATs in six CU STEM departments. These DATs have shown promise in creating structural changes, and additional departments at CU have already expressed interest in running DATs. The proposed work involves continuing to study and enact DATs at CU and expanding the DAT model to Colorado State University (CSU).

Our data suggest that H 2 S donors treatment can compromise the stem cell phenotype and restore thyroid-specific gene expression of ATC cells by targeting AKT-SOX2 pathway, which may serve as a therapeutic strategy to intervene the CSC progression of ATC.

In this pilot phase of the DAT model, we successfully launched six DATs in STEM departments at CU Boulder. We also developed the first iteration of our Core Principles and incorporated ideas from the change literature into the model.

2016年6月24日 · Diallyl trisulfide (DATS), a metabolic byproduct of garlic, is known to inhibit the growth of breast cancer cells in vitro and in vivo. This study demonstrates that DATS targets breast cancer stem cells (bCSC).