DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear …

DAX1 was initially identified as part of a contiguous gene syndrome and is known to function in the proper formation of the adult adrenal gland. It has been hypothesized that DAX1 is …

DAX1 (locus: Xp21.2) encodes a nuclear receptor required for testis, ovary, adrenal, and gonadotroph differentiation. DAX1 duplications result in dosage-sensitive sex reversal by …

DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1; also known as NROB1, nuclear receptor subfamily 0, group B, member 1) encodes a …

The NR0B1 gene provides instructions for making a protein called DAX1. Learn about this gene and related health conditions.

2005年9月1日 · Here, we review DAX1/Dax1 known functional roles and the recently hypothesized function in the development of the embryo and in the maintenance of embryonic …

2023年5月29日 · Here the authors report that estrogen receptor alpha (ERα) interacts with the genome and the nuclear receptor co-repressor NR0B1 (DAX1) to manifest region-specific …

DAX1 (NR0B1) is a nuclear receptor with a characteristic C-terminal ligand binding domain, but an atypical DNA binding domain. Mutations in the DAX1 gene cause adrenal hypoplasia …

2004年9月1日 · DAX1 (dosage sensitive sex reversal (DSS), adrenal hypoplasia congenita (AHC) critical region on the X chromosome, gene 1) encoded by the gene NR0B1, is an unusual …

DAX1基因是1994年克隆出来的孤核受体家族的成员，其主要参与下丘脑-垂体-肾上腺轴/性腺轴的功能，近年来有研究发现该基因在胚胎干细胞以及肿瘤的发生过程中也发挥着重要作用。 …