2019年1月7日 · pCO2 gap is a surrogate for cardiac output; pCO2 gap = PcvCO2 – PaCO2; pCO2 gap >6 mmHg suggests a persistent shock state that may be amenable to fluid resuscitation +/- intrope support; a “ScvO2-cvaCO2gap-guided protocol” has been proposed by Vallet et al (2013) to guide the management of septic shock; RATIONALE. From …

2021年8月31日 · In this chapter, we present the physiological and pathophysiological determinants of the Pv-aCO 2 gap and review its implications in the clinical assessment of circulatory shock. Under aerobic conditions, CO 2 is produced at the mitochondrial level as a by-product of substrate oxidation (pyruvate and citric acid cycle intermediates) (Fig. 1).

The PCO2 gap is an important hemodynamic variable in the management of sepsis-induced circulatory failure. The PCO2 gap can be a marker of the adequacy of the cardiac output status in severe sepsis. A high PCO2 gap value (>0.8 kPa) can identify situations in which increasing CO can be attempted with fluid resuscitation in severe sepsis.

The parameter pCO 2 delta has been more frequently assessed in the management of patients with severe sepsis during the last few years. The studies demonstrate its correlation to mortality and other clinical outcomes, defining pCO 2 delta as a useful tool in the management of the …

Results: The DeltaPCO2/C (a-v)O2 ratio was higher in those with increased ( n=73) than in the normolactatemic group (2.0+/-0.9 vs. 1.1+/-0.6, p<0.0001). Among all the O2- and CO2-derived parameters the DeltaPCO2/C (a-v)O2 ratio had the highest …

2019年9月1日 · In a retrospective data analysis in a large sample of adult post cardiac surgery patients treated in the ICU, we observed that admission central venous-arterial delta-pCO 2 independently predicts ICU mortality. Delta-pCO 2 might thus contribute risk stratification in ICU patients after cardiac surgery. Veno-arterial CO2 difference.

2022年5月2日 · Delta Pco2 after 6 hours of resuscitation of <6 mm Hg indicates normalization of tissue perfusion during pediatric septic shock management. It could be used as a complementary tool to guide the resuscitation in the early phase of pediatric septic shock.

There is an inverse relationship between cardiac output and the central venous-arterial difference of partial pressures of carbon dioxide (pCO2 gap), and pCO2 gap has been used to guide early resuscitation of septic shock. It can be hypothesized ...

2006年6月1日 · Under physiological conditions, Delta PCO2 ranges from 2 to 5 mmHg. The Delta PCO2 depends on carbon dioxide and cardiac output by a complex fashion. In this article, we detail the influence of...

2021年5月13日 · ΔPCO 2 /ΔO 2 was able to depict the occurrence of anaerobic metabolism in both tissue hypoxia models. However, at very low DO 2 values, ΔPCO 2 /ΔO 2 did not only reflect the ongoing anaerobic...