
eDISH (evaluation of Drug-Induced Serious Hepatotoxicity) is a well described method/tool that visually represent liver laboratory data of ALT/AST and Total Bilirubin in form of graph by displaying peak levels for each subject. This is often known as eDISH plots.
The Dish - Wikipedia
The Dish is a 2000 Australian historical comedy-drama film that tells the story of the Parkes Observatory 's role in relaying live television of humanity's first steps on the Moon during the Apollo 11 mission in 1969. It was the top-grossing Australian film in 2000.
Evaluation of drug-induced serious hepatotoxicity (eDISH ... - PubMed
A total of 143 (2.33%) rivaroxaban subjects and 223 (3.64%) enoxaparin subjects experienced a peak ALT >3 × upper limit of normal (ULN) but did not experience an elevation of TB >2 × ULN; these subjects are displayed in the right lower quadrant of the eDISH plot, termed the 'Temple's Corollary quadrant'.
Interactive Safety eDISH graphic - GitHub
Evaluation of Drug-Induced Serious Hepatotoxicity, or eDISH, plots are a key tool used to assess liver toxicity in clinical trials. Standard properties and workflows for static eDish plots are well documented by Watkins et al., Merz et al. and others.
In this paper, the author describes the creation of a visualization tool with drill-down capabilities for detailed study of the rare cases of special interest to implement an innovative method that is well recognized in the medical community for DILI assessment.
This paper will provide details from the SAS macro that is developed to simplify and automate the challenging and tedious process of creating an eDISH plot. This could immensely help programmers streamline the generation of eDISH plot and enhance reproducibility.
eDISH plot is a simple but very informative tool for medical reviewers that enables them to view individual lab patient data, study data or pooled data over time.
The Dish (2000) - Plot - IMDb
Parkes (Australia), has a huge dish in the middle of a sheep paddock. It will transmit the first landing of humanity on the Moon, and the famous Neil Armstrong's moonwalk.
GitHub - FDA/Composite-eDish-Plot: Shiny app for Composite eDISH plot ...
The composite eDISH plot is a visualization of peak on-treatment changes in liver test results both as multiples of the upper limit of normal (xULN) and multiples of the subjects' baseline (xBLN) values in clinical trials of subjects with abnormal baseline values.
eDISH (evaluation of DrugInduced Serious Hepatotoxicity) plot …
Fig. 6 shows the simulated eDISH plot (15) for the proposed clinical protocol of 200/100 mg split daily doses of lixivaptan. At supratherapeutic doses of 400 mg BID for 7 days, 7/285 (2.46%) of...
- 某些结果已被删除