2025年2月11日 · Diabetic kidney disease (DKD) represents the predominant and severe microvascular complication associated with diabetes, frequently culminating in End-Stage Kidney Disease (ESKD). The escalating prevalence of diabetes has correspondingly led to a rise in DKD incidence, imposing significant challenges on both individuals and society.

Diabetic kidney disease (DKD) is the major cause of end-stage kidney disease. However, only renin-angiotensin system inhibitor with multidisciplinary treatments is effective for DKD. In 2019, sodium-glucose cotransporter 2 (SGLT2) inhibitor showed ...

2024年3月7日 · Diabetic kidney disease (DKD) is a major cause of chronic kidney disease (CKD), and it heightens the risk of cardiovascular incidents. The pathogenesis of DKD is thought to involve hemodynamic, inflammatory, and metabolic factors that converge on the fibrotic pathway.

2024年12月16日 · 糖尿病肾脏疾病（DKD）是糖尿病最常见的并发症之一，已成为我国慢性肾脏病的首要病因。 由于基层医院医疗资源欠缺、患者健康意识薄弱，呈现 DKD检出率及治疗率低、血糖控制达标率低、进展速度快 的特点，规范诊治与随访管理已迫在眉睫。 糖尿病患者出现下列情况之一： 随机尿白蛋白/尿肌酐比值（UACR）≥30 mg/g或尿白蛋白排泄率（UAER）≥30 mg/24h，且在3～6个月内重复检查3次UACR或UAER中有2次达到或超过临界值；排除感染等 …

Diabetes is a major public health challenge and diabetic kidney disease (DKD), a broader diagnostic term than diabetic nephropathy, is the leading cause of chronic kidney disease and end-stage kidney disease in the United States and worldwide. A better understanding of the underlying pathophysiologi …

2024年10月14日 · 糖尿病肾脏病（DKD）是我国的常见病与多发病，同时也是引起终末期肾脏病的主要原因，加强DKD早期防治具有重要意义。 目前国内外已颁布了多个针对DKD诊断、治疗及管理的临床指南或专家共识，为临床防治DKD提供了重要指导意见，但对DKD患者这一特殊人群，规范诊疗、细化管理、合理用药等问题仍需不断完善。 主任医师，博士生导师，天津医科大学朱宪彝纪念医院党委副书记，天津市优秀科技工作者、津门医学英才、天津名医。 兼任中国医师协 …

Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide and the single strongest predictor of mortality in patients with diabetes. DKD is a prototypical disease of gene and environmental interactions. Tight glucose control significantly decreases DKD incidence, indicating that …

3 天之前 · Background This study aimed to evaluate the associations between neutrophil percentage-to-albumin ratio (NPAR) and both all-cause and cardiovascular mortality in diabetic kidney disease (DKD) patients. Methods The data for this study were sourced from the National Health and Nutrition Examination Survey (NHANES) 1999–2018. Weighted logistic regression, Cox proportional hazards model, and ...

2018年1月14日 · DKD的诊断是基对肾小球滤过率（eGFR）、白蛋白尿和糖尿病病程、糖尿病视网膜病变等临床表现的综合评估。 临床上，根据持续性的尿白蛋白肌酐比≥30 mg/g和/或伴eGFR<60 ml/min/1.73 m 2 而定。 对于1型糖尿病患者，在确定诊断后5年开始进行每年筛查；对于2型糖尿病患者，在确定诊断后需进行每年筛查。 对于有白蛋白尿的患者，有糖尿病视网膜病变强烈提示存在DKD。 对于白蛋白尿的检测，推荐使用晨尿的尿白蛋白肌酐比测试。 eGFR的估 …

糖尿病肾病（DKD）是指由糖尿病所致的 CKD，病变可累及全肾（包括肾小球、肾小管、肾间质等），主要表现为尿白蛋白/肌酐比值（UACR）≥ 30 mg/g 和（或）估算的...