2024年3月29日 · 弥漫大B细胞淋巴瘤（DLBCL）是血液淋巴造血系统恶性肿瘤，全球每年约有15万新发病例，占所有非霍奇金淋巴瘤（NHL）的30%左右。 患者通常表现为进行性淋巴结肿大和/或淋巴结外病变，一经诊断需要尽早治疗。 大多数患者就诊时已为III期或IV期，60%左右的早期患者可通过R-CHOP（利妥昔单抗、环磷酰胺、多柔比星、长春新碱和泼尼松）免疫化疗方案治愈。 而R-CHOP方案治疗失败的患者，尤其是一线或挽救方案难治性患者，通常预后不良。 在新 …

2025年2月17日 · Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma. Diffuse large B-cell lymphoma is sometimes associated with immunodeficiency, including acquired immunodeficiency syndrome (AIDS).

2017年2月2日 · We evaluated the surveillance imaging role in relapse detection and reviewed its impact on survival for relapsed patients, and found that current imaging approaches do not detect most relapses prior to clinical signs and symptoms or improve survival.

2023年11月2日 · Diffuse large B cell lymphoma (DLBCL) is an aggressive hematological malignancy, and a common histological form of non-Hodgkin's lymphoma. However, its extra-nodal presentation is seen in 30-40% of cases with involvement of gastrointestinal tract, skin, testes, adrenals and bone.

2023年4月24日 · Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma, accounting for about 25% to 30% of all the non-Hodgkin lymphomas. It typically presents as a rapidly growing mass or enlarging lymph nodes in a nodal or extranodal site.

2024年12月27日 · This study aimed to identify the prognostic value of interim 18F-FDG PET/CT (I-PET) for germinal center B-cell-like (GCB) and non-GCB diffuse large B-cell lymphoma (DLBCL), respectively. Baseline 18F-FDG PET/CT (B-PET) and I-PET scans were performed in 112 patients with DLBCL.

2021年12月13日 · Diffuse large B-cell lymphoma (DLBCL) is the commonest non-Hodgkin lymphoma encountered by hematopathologists and oncologists. Management guidelines for DLBCL are developed and published by countries with high income and do not cater for practical challenges faced in resource-constrained settings.

Diffuse Large B Cell lymphoma (DLBCL) is a group of blood cancers that changes certain blood cells in your body called B-cell lymphocytes (B-cells). It usually starts when B-cells in your lymph nodes (sometimes called glands) and your lymphatic system become cancerous.

2025年3月13日 · CT scanning. CT scans of the neck, chest, abdomen, and pelvis are used to help identify the degree of lymphadenopathy, the presence or absence of extranodal disease, and/or the presence of...

循环肿瘤DNA（Circulating Tumor DNA，ctDNA）检测是DLBCL临床诊疗中的重要方法，在分子分型、风险预测、用药指导、动态监测以及预后评估等方面起重要作用。 本期将通过几篇代表性临床研究，基于ctDNA不同技术平台，系统性地介绍其在DLBCL治疗中的应用场景。 1.液体活检用于弥漫性大B细胞淋巴瘤突变图谱和克隆进化研究. 受限于临床肿瘤活检组织获取困难，在DLBCL患者治疗时通过基因检测结果进行预后和疗效评估不易，且常规在耐药之后取一系列的活检组织进 …