DOCK8 deficiency is a rare immune disorder named after the mutated gene responsible for the disease. NIAID researchers discovered the cause of DOCK8 deficiency in 2009. People with …

DOCK8 deficiency, also called DOCK8 immunodeficiency syndrome, is the autosomal recessive form of hyperimmunoglobulin E syndrome, a genetic disorder characterized by elevated …

DOCK8 immunodeficiency syndrome is a rare genetic disorder of the immune system characterized by recurrent viral infections of the skin and respiratory system. People with …

2024年12月24日 · DOCK8 (Dedicator Of Cytokinesis 8) is a Protein Coding gene. Diseases associated with DOCK8 include Hyper-Ige Syndrome 2, Autosomal Recessive, With Recurrent …

Dedicator of Cytokinesis 8 (DOCK8) deficiency is a combined immunodeficiency that exemplifies the broad clinical features of primary immunodeficiencies (PIDs), extending beyond recurrent …

dock8免疫缺陷综合征是由dock8基因突变引起的。 由该基因产生的蛋白质在几种类型的免疫系统细胞的存活和功能中起关键作用。 DOCK8蛋白的功能之一是帮助维持称为T 细胞的免疫细胞 …

2017年4月3日 · DOCK8 deficiency in humans results in the onset of combined immunodeficiency disease (CID), clinically associated with chronic infections with diverse microbial pathogens, …

Dedicator of cytokinesis protein 8 (Dock8) is a large (~190 kDa) protein encoded in the human by the DOCK8 gene, involved in intracellular signalling networks. [5] It is a member of the DOCK …

DOCK8 immunodeficiency syndrome is characterized by abnormally high levels of an immune system protein called immunoglobulin E (IgE) in the blood; the levels can be more than 10 …

More than 130 mutations in the DOCK8 gene have been found to cause DOCK8 immunodeficiency syndrome (also called autosomal recessive hyper-IgE syndrome or AR …