2022年8月8日 · What is Webb’s Depth of Knowledge definition? Based on his 1997 study, Webb’s Depth of Knowledge is a framework that categorizes contexts — prompts, scenarios and …

2024年12月24日 · DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 …

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical …

2016年9月23日 · Dok-1 和 Dok-2 是在 T 细胞中表达的 Dok 家族的两个成员，它们在体外负向调节 TCR 信号。 然而，Dok 蛋白在体内调节 T 细胞功能的作用尚未研究。 我们研究了 Dok-1 和 …

2022年5月1日 · Phosphorylated Dok-1 inhibits FcεRI-operated calcium influx, and negatively regulated degranulation by inhibiting calcium-dependent disassembly of actin filaments. Our …

Dok-1抗体（A-3）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和免疫组织化学检测小鼠、大鼠和人类来源的Dok-1蛋白。

We tested the functional importance of Dok-1 and Dok-2 for viral replication during acute HSV-1 infection using a murine model of ocular infection. Dok-1 and Dok-2 double-knockout (DKO) …

很多科学家认为嗜碱性粒细胞酪氨酸激酶下游分子(Dok)-1通过激活FcγRIIB抑制受体来抑制FcεRI诱发的脱颗粒信号反应。 前期研究发现Dok-1可以直接被FcεRI受体激活，进而调节细胞脱颗粒 …

The adaptor protein Dok-1 is known to have an essential role in the negative regulation of a variety of cytokine signalling events. However, here we have found that the loss of Dok-1 …

2017年7月12日 · In this study, we examined the involvement of Dok-1 and Dok-2 signaling proteins in the control of HSV-1 infection. We provide evidence that Dok proteins are required …