2024年12月24日 · DOK2 (Docking Protein 2) is a Protein Coding gene. Diseases associated with DOK2 include Histiocytic And Dendritic Cell Cancer and Leukemia. Among its related …

DOK2 is a well-known tumor suppressor gene located on human chromosome 8p21.3 whose expression is downstream of tyrosine kinase, thereby affecting EGF-stimulated DOK2 …

2021年11月29日 · The review focuses on the role of DOK2 in multiple tumor types in the lungs, intestines, liver, and breast. Additionally, we discuss the potential mechanisms of action of …

2022年2月1日 · DOK plays a role of tumor suppressor gene or tumor-promoting gene in different tumors. However, DOK family genes play a role in promoting cancer in UVM. DOK family …

Gene target information for DOK2 - docking protein 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Dok-2 is a critical element of a linker for activation of T cells (LAT)-dependent negative feedback loop that attenuates early T-cell receptor (TCR) signal. DOK1 and DOK2 interact with the Tec …

由该基因编码的蛋白质在从慢性粒细胞白血病 (CML) 慢性期患者分离的造血祖细胞中组成型酪氨酸磷酸化。 它可能是 p210 (bcr/abl) 的关键底物，p210 (bcr/abl) 是一种嵌合蛋白，其存在与 …

2022年3月7日 · We suggest that elevated DOK2 expression could be an unfavorable prognostic indicator of survival in patients with AML. Our findings provide new insights into the role of …

Downstream of kinase protein 2 (Dok2) is adaptor protein known to modulate the effect of tyrosine kinase. Previously, Dok2 is shown to be marker of poor prognosis in colorectal and gastric …

2022年9月29日 · Dedicator of cytokinesis 2 (DOCK2) can activate the downstream small G protein Rac and regulate cytoskeletal reorganization. DOCK2 is essential for critical …