
Nutritional state-dependent modulation of Insulin-Producing
2024年12月19日 · Drosophila Insulin-Producing Cells (IPCs) are functional analogues to mammalian pancreatic beta cells and release insulin directly into circulation. IPC activity is …
Drosophila FIT is a protein-specific satiety hormone essential for ...
2017年1月19日 · Here we report that in Drosophila, protein intake-induced feeding inhibition (PIFI) is specific to protein-containing food, and this effect is mediated by a fat body (FB) peptide …
Nutritional state-dependent modulation of insulin-producing cells in
2025年1月29日 · Drosophila insulin-producing cells (IPCs) are functional analogues of mammalian pancreatic beta cells and release insulin directly into circulation. To investigate the …
Modeling metabolic homeostasis and nutrient sensing in Drosophila …
The imaginal morphogenesis protein-Late 2 (Imp-L2), which is a neural/ectodermal development factor in Drosophila, has been shown to bind to DILP2 and DILP5 to impair insulin signaling …
A gut-derived hormone suppresses sugar appetite and regulates food …
2022年11月7日 · Gut-derived NPF acts on glucagon-like adipokinetic hormone (AKH) signalling to induce sugar satiety and increase consumption of protein-rich food, and on adipose tissue to …
Nutrient control of Drosophila longevity - PMC - PubMed …
Drosophila appear to modulate lifespan upon DR by responding to reduced proportion of nutrient amino acids relative to carbohydrates, and not in response to the absolute quantify of either …
A brain-derived insulin signal encodes protein satiety for nutrient ...
2024年6月25日 · However, whether insulin signals can encode a certain type of nutrients to regulate nutrient-specific feeding behavior remains elusive. Here, we show that in female …
The Dilemmas of the Gourmet Fly: The Molecular and Neuronal …
The emerging picture of how feeding decisions are modulated in Drosophila is that upon changes in nutrient state, both peripheral chemosensory and central neurons change their firing …
Neuronal processing of amino acids in Drosophila : from taste …
2019年7月26日 · Most studies on protein or amino acid feeding in Drosophila focus on adult flies. However, larvae too are able to choose food with the optimal protein–carbohydrate ratio to …
Nutrient control of Drosophila longevity - ScienceDirect
2014年10月1日 · Drosophila appear to modulate lifespan upon DR by responding to a reduced proportion of nutrient amino acids relative to carbohydrates, and not in response to the …