Often considered as a serendipitous approach, where repurposable drugs are discovered by chance, drug repurposing has heavily benefited from advances in human genomics, network …

Drug repurposing has become the need of time to fasten the drug discovery process and find quicker solutions to the over-exerted healthcare scenario and drug needs. Drug repurposing …

2018年10月12日 · In this Review, we present approaches used for drug repurposing (also known as drug repositioning), discuss the challenges faced by the repurposing community and …

Learn more about drug repurposing and how it can be used to quickly identify compounds with an established safety profile and known therapeutic advantages.

In this Review, we present approaches used for drug repurposing (also known as drug repositioning), discuss the challenges faced by the repurposing community and recommend …

2023年10月19日 · Drug repurposing is an alternative strategy that allows to reduce the time and costs of pharmaceutical research in which new uses are identified for drugs already approved …

2021年9月22日 · Drug repurposing (or drug repositioning) (1–6) aims to take a drug that has undergone extensive safety and efficacy testing and redirect it for an additional or unrelated …

2024年8月29日 · “Drug repurposing” is a cutting-edge technique that entails pharmaceuticals already available on the market and has completed essential phases of development. The …

Drug repurposing is an alternative strategy that allows to reduce the time and costs of pharmaceutical research in which new uses are identified for drugs already approved or under …

2014年8月8日 · Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs—a …

Drug repurposing is a cost-effective and time-saving method for enhancing the number of clinically available drugs to treat cancer, thereby contributing to the development of more …

2019年10月1日 · Drug repurposing could arise from serendipitous observations or exploiting side effects. Today, researchers have addressed drug repurposing in a systematic manner but …

At the National Center for Advancing Translational Sciences (NCATS), drug repurposing is a key strategy for bringing more treatments for all people more quickly. Drug repurposing finds …

2024年3月4日 · Drug repurposing, also referred to as drug repositioning or reprofiling, is an approach that identifies new clinical applications for approved or investigational drugs outside …

2024年6月26日 · Policy-makers in the United States and Europe have created seven drug development programs that aim to overcome these challenges using a variety of different …

2025年2月25日 · However, drug repurposing is a progressive step in identifying new therapeutic uses of existing drugs. It has emerged as a promising strategy in the quest to combat AD. …

Drug repurposing holds the potential to bring medications with known safety profiles to new patient populations. Numerous examples exist for the identification of new indications for …

5 天之前 · Repurposing apoptotic inducer drugs as potential M. tuberculosis agents may be an interesting approach to combat the pathogen and facilitate its clearance through apoptosis …

2024年6月27日 · Explore how repurposing drugs are proving to be the key to unlocking undruggable targets, faster trials, and reduced costs. Drug repurposing is an approach that, …

Drug repurposing (DR) is used routinely in oncology. Both oncology and non-oncology drugs are used as monotherapy or in combination therapy to enhance other therapeutic options across …

4 天之前 · Although drug repurposing (DR) represents a valuable and attractive strategy for the treatment of pancreatic cancer (PC), several limitations to advance the field were identified …

2025年2月25日 · Cholesterol Drug Repurposed as Investigational Therapy for HPV+ Cancers at University Hospitals Seidman Cancer Center in Nation’s First-Ever Clinical Trials. ... Patients …

Because of the high risk, substantial cost and slow pace of new drug discovery and development, drug repurposing (also called repositioning, redirecting, reprofiling) is becoming an attractive …

2025年2月23日 · Repurposing amlodipine, a commonly used blood pressure medicine, could help manage attention-deficit/ hyperactivity disorder (ADHD) symptoms, according to an …

4 天之前 · Researchers observed that this drug effectively mitigates the adverse effects of HPV-associated oncoproteins, specifically enhancing the function of the p53 tumor suppressor …

Repurposing is a drug development strategy receiving heightened attention after the Food and Drug Administration granted emergency use authorization of several repurposed drugs to treat …

6 天之前 · Eli Lilly, the maker of blockbuster weight loss and diabetes drugs Zepbound and Mounjaro, said it will invest an additional $27 billion to build four new manufacturing plants in …

Drug repurposing—also known as drug repositioning, re-profiling, re-tasking or therapeutic switching (3, 4)—is the process of discovering new indications for already approved drugs to …