DTPA stands for diethylenetriamine pentaacetic acid. GFR stands for glomerular filtration rate. The GFR tells how much blood passes through your glomeruli each minute. Glomeruli are the tiny filters in the kidneys that remove waste from the blood. This study will show the GFR for each of your kidneys. How does the study work?

Glomerular filtration rate calculated both by clearance of 1251-iothalamate from urine and plasma (x-axis) and by clearance of 99"'Tc-DTPA from two protein-free plasma samples (y-axis). Data have been sorted by the iothalamate method for values of GFR > 20 ml/m.

2013年6月1日 · This article reviews available radionuclide-based techniques for glomerular filtration rate (GFR) measurement, focusing on clinical indications for GFR measurement, ideal GFR radiopharmaceutical tracer properties, and the 2 most common tracers in clinical use.

2019年6月14日 · Two-sample method (GFR dt) and 99m Tc-DTPA dynamic renal imaging (GFR Gates) were used for determination of the GFR. We took GFR dt as the reference method, and then took the peak time of blood perfusion phase as the new time origin to ensure that all patients were unified on the time-radioactivity count rate curve.

Glomerular filtration rate (GFR) is considered to be the best parameter to assess the overall kidney function. GFR can be measured by calculating the plasma clearance of various glomerular filtration markers like inulin, ethylene-diamine-tetra-acetic-acid, diethylene-triamine-penta-acetic acid (DTPA), iothalamate and iohexol.

A systematic review from Soveri et al1 concluded that plasma clearance of 99mTc–diethylenetriaminepentaacetic acid (99mTc-DTPA) is inaccurate for measuring glomerular filtration rate (GFR).

2017年5月17日 · Gate’s glomerular filtration rate (gGFR) measured by 99m Tc-DTPA renal dynamic imaging and estimated GFR (eGFR) estimated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation are two indexes used to evaluate renal function.

2023年2月27日 · Tc-99m DTPA (diethylene-triamine-pentaacetate) is one of the technetium radiopharmaceuticals used in renal imaging and primarily used to measure the glomerular filtration rate (GFR). Characteristics. photon energy: 140 KeV. physical half-life: 6 hours. oxidation state of technetium: +4. biological half-life: 2.5 hours. normal distribution ...

Aim: Sufficient glomerular filtration rate (GFR) is mandatory in living kidney donors (LKD) before renal transplantation (RT). Guidelines recommend exogenous GFR (e. g. Tc-99m-DTPA) besides estimated GFR by plasma creatinine (eGFR). Tc-99m-MAG3 determines split function and tubular extraction rate (TER).

Several publications compare plasma clearance of 99mTc-DTPA to 51Cr-EDTA, and all demonstrate good overall precision and minimal bias (median bias 1%; P30 93%; P10 72%; Fig 1).4-6 , 5 In both included studies,2,3bias was large (14% and 24.8%), and 5. (r 0.694). Given subsequently published data, the measurements.