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Effective Administration Route for the Deleted Form of Hepatocyte ...
1999年1月1日 · These observations suggest that iv administration is the most effective in exerting the pharmacological effects of dHGF among three administration routes. dHGF after iv …
Secretory expression and characterization of a recombinant …
HGF is a disulfide-linked heterodimer derived by proteolytic cleavage of the human pro-hormone between amino acids R494 and V495. This cleavage process generates a molecule composed …
The five amino acid-deleted isoform of hepatocyte growth factor ...
1999年2月8日 · We report the generation and analysis of transgenic mice overexpressing the five amino acid-deleted variant of HGF (dHGF) in the liver by virtue of an albumin expression vector.
Continuous intravenous infusion of deleted form of hepatocyte …
2001年6月1日 · We investigated the action of a deleted form of HGF (dHGF) on hepatic IR injury in rats. Methods: dHGF or phosphate-buffered saline was continuously infused intravenously …
Antifibrogenic effect of a deletion variant of hepatocyte growth …
1996年9月1日 · In this report we assessed the efficacy of the treatment of hepatic fibrosis with a naturally occurring deletion variant of hepatocyte growth factor (dHGF). The administration of …
Transplantation of human hepatocytes cultured with deleted …
2005年5月27日 · As a tool for maintaining hepatocyte functions in vitro, dHGF, a variant of HGF (hepatocyte growth factor) with a deletion of five amino acids, attracted our attention because …
A deleted form of human hepatocyte growth factor stimulates …
Here we report the effect of the recombinant human deleted form of hepatocyte growth factor (dHGF) on lipid metabolism in rats. In primary cultured rat hepatocytes, dHGF accelerated …
Tri-iodothyronine and a deleted form of hepatocyte growth factor …
2000年5月15日 · Acting synergistically, T3 and a truncated form of recombinant hepatocyte growth factor (dHGF) induced 30% of hepatocytes in normal rat liver to enter DNA synthesis at …
Analysis of deleted variant of hepatocyte growth factor by alanine ...
1998年8月28日 · To understand the structure-function relationship of hepatocyte growth factor (HGF) in more detail, we analyzed one of the other forms of HGF, deleted variant of HGF …