Dynein is involved in the movement of chromosomes and positioning the mitotic spindles for cell division. [2] [3] Dynein carries organelles, vesicles and possibly microtubule fragments along the axons of neurons toward the cell body in a process called retrograde axonal transport. [1]

高能蛋白（英語： Dynein ）是一种马达蛋白（或分子马达），可将ATP高能磷酸键的化学能转化为机械能。 动力蛋白依靠在 微管 上向负端的“行走”运输细胞内的货物。

2013年9月25日 · Establishes S. cerevisiae as another important cytoplasmic dynein expression system and provides insight into the requirements for processive dynein motion.

Dynein is the primary motor responsible for motility and force generation toward the minus ends of microtubules (MTs) (124, 150) and drives a myriad of cellular processes in eukaryotes (69, 136, 138).

2025年1月2日 · Dynein is a minus-end-directed microtubule motor protein, which transports a variety of intracellular cargo by hydrolysing ATP to power its movement along microtubule tracks.

Dynein is a large cytoskeletal motor protein that belongs to the AAA + (ATPases associated with diverse cellular activities) superfamily. While dynein has had a rich history of cellular research, its molecular mechanism of motility remains poorly understood.

2023年12月18日 · In this primer, we first highlight the structure, mechanism, and regulation of dynein-1, which is the best-characterized member of the dynein motor family, and then describe the unique features and cellular roles of other dyneins.

2023年12月18日 · Dyneins are a family of motor proteins that carry out motility and force generation functions towards the minus end of microtubule filaments. Cytoplasmic dynein (dynein-1) is responsible for transporting intracellular cargos in the retrograde direction in the cytoplasm, anchoring several organelles …

2018年4月16日 · Cytoplasmic dynein is a minus-end-directed microtubule-based motor that transports a wide range of cargoes, including organelles, RNAs, protein complexes and viruses.

Dynein is a microtubule-based molecular motor that is involved in various biological functions, such as axonal transport, mitosis, and cilia/flagella movement. Although dynein was discovered 50 years ago, the progress of dynein research has been ...