2024年12月24日 · DYNLL1 (Dynein Light Chain LC8-Type 1) is a Protein Coding gene. Diseases associated with DYNLL1 include Rabies and Lissencephaly 1. Among its related pathways are …

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks …

2018年10月31日 · In cells, DYNLL1 limits nucleolytic degradation of DNA ends by associating with the DNA end-resection machinery (MRN complex, BLM helicase and DNA2 …

Dynein light chain LC8 alleviates nonalcoholic steatohepatitis by inhibiting NF-kappaB signaling and reducing oxidative stress. DYNLL1 is hypomethylated and upregulated in a tumor stage- …

细胞质动力蛋白是分子量约为 1,200 kD 的大型酶复合物。 它们包含两个主要由动力蛋白重链形成的力产生头，以及将头连接到基底域的茎，基底域包含数量不等的辅助中间链。 该复合物参 …

2024年1月4日 · 摘要：dynll1蛋白是一种重要的动力蛋白轻链，参与细胞运动、形态变化和细胞器的定位等生物学过程。 它能够调控微管的聚合和解聚，影响细胞定位运动、分裂和迁移等。

2023年9月11日 · Here we describe how the 53BP1-associated protein DYNLL1 works in tandem with the Shieldin complex to protect DNA ends. DYNLL1 is recruited to DSBs by 53BP1, …

2019年4月22日 · To define the contribution of the LC8-type dynein light chain subunit to the CD2 complex, we have generated Dynll1 -deficient mouse strains, including the first-ever …

2020年11月8日 · In cells, DYNLL1 limits nucleolytic degradation of DNA ends by associating with the DNA end-resection machinery (MRN complex, BLM helicase and DNA2 endonuclease). In …

DLC 1 (also known as DYNLL1, LC8, and PIN) is ubiquitously expressed and participates in a variety of essential intracellular events. DLC1 transition from monomer to dimer is crucial for …