Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. However, all four elements of this tetrad are not required for diagnosis.

2024年7月15日 · Henoch-Schönlein purpura (HSP) is a disease that inflames small blood vessels. The inflammation causes blood vessels in the skin, intestines, kidneys, and joints to start...

2020年8月15日 · Immunoglobulin A (IgA) vasculitis, formerly known as Henoch-Schönlein purpura, is defined as a systemic, immune complex–mediated, small-vessel leukocytoclastic vasculitis...

2023年4月19日 · Henoch-Schönlein purpura (HSP): IgA vasculitis presenting with glomerulonephritis, abdominal pain, arthralgia, and purpura; most common vasculitis in children, incidence 20 per 100,000. Aetiology: immune-mediated small vessel vasculitis with IgA and complement deposits in vessel walls; often follows an upper respiratory tract infection (URTI).

Henoch-schonlein purpura (HSP) is an IgA-mediated systemic small vessel vasculitis. It is the most common form of systemic vasculitis in children. A 9 years old girl admitted to the hospital with chief complain of purplish red rash on both legs since approximately 1 week with painful knees and ankles that make the patient unable to walk.

A first episode of HSP, in the absence of significant renal disease, usually resolves within 4 weeks. Rash is often the last symptom to remit; Joint pain usually resolves spontaneously within 72 hours; Uncomplicated abdominal pain usually resolves spontaneously within 24-48 hours

Henoch-Schonlein purpura (HSP) is disease that causes small blood vessels to become swollen and irritated—a condition called vasculitis. It is most common in children between the ages of 3 and 15 years old and is rarely seen in adults.

Henoch-Schönlein purpura (HSP) is the most common cause of vasculitis in children. The incidence of HSP in China is 8.13–14.06/100000 children. 1,2 The most challenging aspect of HSP is determining the specific trigger for leukocytoclastic vasculitis. Associations with bacterial and viral infection and immunisation have been reported. 1,3,4.

Abbreviation: HSP Classical triad of non-thrombocytopenic palpable purpura , abdominal pain , arthritis Most common vasculitis in childhood (usually 2-11 yr)

Henoch-Schonlein purpura (HSP) is a multisystem disorder affecting mainly the skin, joints, gastro-intestinal tract and kidneys. Involvement of other organs (pulmonary haemorrage and CNS involvement) is rare. The extrarenal manifestations are due to …