E2F1 - Wikipedia
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins …
E2F1 Gene - GeneCards | E2F1 Protein | E2F1 Antibody
2024年12月24日 · E2F1 (E2F Transcription Factor 1) is a Protein Coding gene. Diseases associated with E2F1 include Retinoblastoma and Squamous Cell Carcinoma. Among its …
癌症中的E2F转录因子家族 - 知乎 - 知乎专栏
细胞周期蛋白依赖性激酶 (CDK)-RB-E2F 调控轴组成了驱动细胞周期进程、决定基因组复制的时间和准确性、并确保遗传物质准确传递的核心转录机制。 该调控轴的最终效应子是编码转录激 …
E2F1: Cause and Consequence of DNA Replication Stress - PMC
E2F transcriptional activators promote the transcription of numerous genes required for S phase entry and DNA synthesis. In fact, E2F-dependent transcription was recently found to …
转录因子E2F1 - 百度百科
转录因子E2F1是由人类E2F1 基因 编码出的蛋白质。 该基因编码出的蛋白质是E2F转录因子家族中的成员。 E2F家族在控制细胞周期及抑癌基因功能上起到重要作用，也是小DNA致癌病毒转 …
E2F 转录因子 1（E2F1）基因 | MCE - MCE-生物活性分子大师
e2f 转录因子 1： 该基因编码的蛋白质是 e2f 转录因子家族的成员。 E2F 家族在控制细胞周期和肿瘤抑制蛋白的作用中起着至关重要的作用，也是小 DNA 肿瘤病毒转化蛋白的靶标。
E2F transcription factor-1 regulates oxidative metabolism
2011年8月14日 · Here, we show that E2F1 coordinates cellular responses by acting as a regulatory switch between cell proliferation and metabolism. In basal conditions, E2F1 …
E2F-1: a proliferative marker of breast neoplasia - PubMed
E2F-1 is the best known ultimate transcription factor in the cyclin/cyclin-dependent kinase/retinoblastoma gene pathway and is probably involved in carcinogenesis and tumor …
E2F1 pathways to apoptosis - PubMed
2002年10月2日 · E2F1-induced apoptosis occurs via multiple pathways, some of which induce stabilization and activation of the tumor suppressor p53. The pro-apoptotic activity of E2F1 …
E2F-1 functions in mice to promote apoptosis and suppress
1996年5月17日 · As E2F-1-/- mice age they exhibit a second phenotype marked by aberrant cell proliferation. These findings suggest that while certain members of the E2F family may …