Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene. [5][6] The protein encoded by this gene is a member of the E2F family of transcription factors.

2024年12月24日 · E2F4 (E2F Transcription Factor 4) is a Protein Coding gene. Diseases associated with E2F4 include Colorectal Cancer and Retinoblastoma. Among its related …

2019年7月3日 · Here we show that E2F4 is important for the proliferation and the survival of mouse embryonic stem cells. In these cells, E2F4 acts in part as a transcriptional activator that …

The E2F family of transcription factors is a key determinant of cell proliferation in response to extra- and intra-cellular signals. Within this family, E2F4 is a transcriptional repressor whose …

E2F4, binding sites are located within 2 kb of a transcription start site, in both normal and tumor cells; By interacting with p130, E2F4 plays a key role in the maintenance of a stable G2 arrest. …

该基因编码的蛋白质是 E2F 转录因子家族的成员。 E2F 家族在控制细胞周期和肿瘤抑制蛋白的作用中起着至关重要的作用，也是小 DNA 肿瘤病毒转化蛋白的靶标。 E2F 蛋白包含几个在大多 …

过去普遍认为E2F4是肿瘤抑制因子，但近年来研究表明，E2F4可促进多种肿瘤的发生、发展和转移。 本文主要对E2F4的结构、功能和在不同肿瘤中的作用及其机制进行综述，以探讨E2F4在 …

The E2F family of transcription factors has important roles in cell cycle progression. E2F4 is an E2F family member that has been proposed to be primarily a repressor of transcription, but the …

E2F4 binds p130 and localizes to the nucleus following PC12 cell differentiation. E2F4 interactions with Rb family proteins have a major impact on E2F4 function, including its …

E2F4 is a member of the E2F family of transcription factors that associates with Rb, p107, and p130, primarily involved in the active repression of E2F-responsive genes. AI generated …