20-Hydroxyecdysone (20E) Primary Response Gene E93 Modulates 20E ...
In general, Br-C, E74, E75, and E93 positively affect 20E signaling (8). As a potent HTH transcription factor, E93 binds several 20E response genes and PCD genes on polytene …
Cross-talk of insulin-like peptides, juvenile hormone, and 20 ... - PNAS
2021年2月1日 · The ecdysone-inducible early gene E74 (Eip74EF) encodes an ETS (erythroblast transformation specific) transcription factor that mediates the 20E response in gene regulation. …
李胜教授团队在PNAS上发表重要研究成果 - 科研进展 - 华南师范 …
2017年12月19日 · 昆虫的变态发育包括幼虫蜕皮和幼虫-蛹-成虫变态，均为蜕皮激素（20-hydroxyecdysone，20E）诱导产生；而倍半萜烯类激素-保幼激素（Juvenile hormone，JH） …
Two isoforms of the early E74 gene, an Ets transcription factor ...
2002年4月25日 · We report characterization of two isoforms of the mosquito early E74 gene (AaE74), which have a common C-terminal Ets DNA-binding domain and unique N-termini. …
Direct and indirect gene repression by the ecdysone cascade …
While indirect repression involves E74, EcR binds to an ecdysone response element different from those utilized in 20E-mediated gene activation to exert direct repressive action. …
The early gene E74B isoform is a transcriptional activator of the ...
2004年4月15日 · Vitellogenesis is regulated by the 20-hydroxyecdysone (20E) regulatory hierarchy, in which the Ets-domain protein E74 is a key transcriptional regulator. The mosquito …
E74 knockdown represses larval development and chitin synthesis in
2022年10月1日 · HcE74 knockdown reduced chitin content in midgut and epidermis. E74 is a key transcription factor induced by 20E, which plays a broad role in many physiological events …
20-Hydroxyecdysone upregulates Atg genes to induce autophagy …
Five Atg genes were potentially 20E primary-responsive, and a 20E response element was identified in the Atg1 (ortholog of human ULK1) promoter region. Furthermore, RNAi …
20-Hydroxyecdysone (20E) Primary Response Gene E93 Modulates 20E ...
2015年11月6日 · Importantly, the two HTH domains in E93 are critical for inducing the expression of a subset of 20E response genes, including EcR, USP, E74, Br-C, and Atg1. By contrast, the …
20-hydroxyecdysone Upregulates Ecdysone Receptor (ECR
2023年6月26日 · We found that ECR gene expression peaked in the 7-day-old larvae, then decreased gradually from the pupae stage. 20E slowly reduced food consumption and then …