Purpose: To determine the underlying pathology and clinical significance of epithelial cell abnormalities (ECA) identified during cervical Papanicolaou (Pap) smear screening. Material and methods: A total of 19,215 Pap smears stained by Papanicolaou stain were screened during a …

2025年3月7日 · Our aim was to evaluate the diagnostic value of Papanicolaou (Pap) test in endometrial cancer (ECa). Methods: ECa cases with liquid-based Pap smears within 6 months before the histological diagnosis were retrospectively searched from an academic women's and children's hospital pathology archive.

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Patients with histologically proven adenocarcinoma in-situ (AIS) or invasive endocervical adenocarcinoma (EAC) over a 17-year-period (1998-2015) were identified. The TPPT immediately preceding the histological diagnosis of AIS/ECA was designated as index Pap (IP).

2024年7月31日 · Our study highlights the potential for early detection of ECA at the AIS stage through the combined use of PAP smear and hrHPV screening tests. The use of both screening methods demonstrated a success rate of 96.9% in detecting AIS cases in our study cohort.

2015年9月23日 · Cervical cancer is preceded by cervical surface epithelial cell abnormalities (ECA) which can be detected by Pap smear test. Simultaneous human papillomavirus and human immunodeficiency virus (HIV) infection increases cervical cancer.

2013年10月1日 · The Pap test is not as sensitive for detection of glandular lesions compared to squamous lesions, making the role of HPV testing particularly important for those interpretations. We reviewed our records for ten years for cases of surgically-proven endocervical adenocarcinoma (ECA) and adenocarcinoma in situ (AIS) with a previous HPV test.

2017年9月1日 · The Tahoe study shows that knowledge of hr-HPV status biases interpretation of Pap results as epithelial cells abnormality (ECA). Cytotechnologists (CT) can sign out Pap tests that are negative for ECA.

We also report for the first time a significant increase in detection of epithelial cell abnormalities (ECA) in Pap tests with HCG as opposed to Pap tests without HCG. We conclude that these observations are best explained by the hypothesis that the presence of HCG in Pap tests most often represents adequate sampling of the transformation zone ...

2018年7月1日 · Pap smear testing is a very useful, simple, economical, and safe tool for detecting precancerous cervical epithelial lesions. It should be established as a routine screening procedure to reduce the treatment burden, morbidity, and mortality.