The EREFS is a scoring system used by healthcare providers that can help evaluate the severity of eosinophilic esophagitis (EoE). The EREFS alone cannot diagnose EoE, but it can help diagnose the condition and monitor it over time.1.

2025年2月19日 · The ACG guidelines for EoE emphasize diagnosis based on symptoms of esophageal dysfunction, biopsy findings (≥15 eosinophils per high-power field), and exclusion of other causes. Endoscopic assessment using the EoE Endoscopic Reference Score (EREFS) 2 …

2017年12月14日 · The EREFS scoring system was proposed and validated as a standardized reporting of endoscopic features of EoE in adults. In this study, we evaluated the utility of EREFS for diagnosis, post-treatment surveillance, and longitudinal treatment response in children with EoE and control subjects.

EoE is a clinicopathological disease for which the histological demonstration of esophageal eosinophilia is essential for diagnosis. Therefore, the recognition of the characteristic endoscopic features with subsequent biopsy are critical for early definitive diagnosis and treatment, in order to prevent complications.

2016年4月11日 · The Eosinophilic Esophagitis Endoscopic Reference Score (EREFS) was recently developed to help standardize reporting of endoscopic findings in patients with eosinophilic esophagitis (EoE; Gut 2013; 62:489). The score takes into account the presence of esophageal edema and strictures and the presence and severity of exudates, rings, and furrows.

In a prospective study of children undergoing diagnostic or post-treatment endoscopy, we found the EREFS to accurately identify those with EoE. Children who responded to therapy had lower EREFS scores than non-responders. EREFSs can be used to measure outcomes of pediatric patients, in conjunction w …

Reference Score (EREFS), and how scores change in response to treatment. We investigated the operating characteristics of the EREFS in diagnosis of EoE, how the score changes with treat-ment, and ways to optimize scoring system. METHODS: We performed a prospective study of adults undergoing outpatient upper endoscopy from

Biomarkers offer a unique and non-invasive approach to tracking EoE disease progression. While no biomarkers have definitively met the diagnostic criteria for eosinophilic GI diseases, some...

The present investigation confirms the utilization of EREFS in Pediatric EoE. Furthermore, EREFS can detect EoE and document response to treatment in both younger and older children. EREFS, however, predicted EoE in the older children with a higher …

2023年4月1日 · The EoE Endoscopic Reference Score (EREFS) was developed as a way to quantify the major endoscopic features of EoE, including edema, rings, exudates, furrows, and strictures (the first letter of these findings also comprises the acronym for the system). EDEMA is graded as absent (grade 0) or present (1; decreased or absent vascularity).