The neurologic considerations focus on the degree of spinal cord compromise and include a radiographic assessment of the degree of epidural spinal cord compression (ESCC) and the clinical assessment of myelopathy and/or functional radiculopathy.

We delineate and provide the evidence for the neurologic, oncologic, mechanical, and systemic (NOMS) decision framework, which is used at Memorial Sloan-Kettering Cancer Center to determine the optimal therapy for patients with spine metastases.

2018年3月2日 · Through tumor spread from the arterial system, epidural venous plexus, cerebrospinal fluid (CSF), or direct extension, symptoms develop secondary to painful vertebral body involvement or neurologic compromise from …

Download scientific diagram | Neurologic, oncologic, mechanical, and systemic (NOMS) decision framework. cEBRT: Conventional external beam radiation therapy; ESCC: Epidural spinal cord...

2023年11月1日 · This review recapitulates the current state-of-the-art, evidence-based data on the treatment of spinal metastases and integrates these data into a decision framework, NOMS, which is based on four sentinel pillars of decision making in metastatic spine tumors: Neurological status, Oncologic tumor behavior, Mechanical stability, and Systemic disea...

2013年5月24日 · We delineate and provide the evidence for the neurologic, oncologic, mechanical, and systemic (NOMS) decision framework, which is used at Memorial Sloan-Kettering Cancer Center to determine the...

Separation surgery is a new concept for metastatic spinal cord compression treatment. Stereotactic radiosurgery increased local control, overcoming radio-resistance’s idea. The surgery goal shifted towards creating targets for radiations avoiding cord damages. Minimal invasive strategies could allow quick return to systemic therapies.

... goal of this decision framework is to provide a rapid, highly reliable assessment (e.g., low-grade extradural spinal cord compression (ESCC) versus high-grade disease or mechanical versus...

2024年5月31日 · NOMS framework: neurologic, oncologic, mechanical instability, systemic illness neurologic: measure of epidural spinal cord compression (ESCC) 0-1 low grade, 2-3 high grade

2013年5月24日 · Over the past 15 years, the multidisciplinary spine team at Memorial Sloan‐Kettering Cancer Center (MSKCC) has developed and used a decision framework for metastatic spine disease, NOMS, which incorporates four fundamental assessments: neurologic, oncologic, mechanical instability, and systemic disease.