2024年3月14日 · Esophageal squamous cell carcinoma (ESCC) remains an important health concern in developing countries. Patients with advanced ESCC have a poor prognosis...

2017年3月14日 · 8th edition clinical staging TNM categories—the facts about cancer—are judged clinically (cTNM) based on imaging studies, with minimal histologic information. This distinguishes them from pathologic cancer facts (pTNM) obtained by and large through microscopic examination of resection specimens.

2021年11月12日 · Here, we selected 94 surgically resected primary tumor tissues (T) and 24 non-tumor esophageal tissues (N) from 94 cases of intermediate- and advanced-stage (TNM II–IV stage) ESCC and performed...

2022年3月14日 · This study aimed to determine distinguished metabolites and metabolic pathways for ESCC progression. We use the ultra-high-performance LC–MS/MS analysis of all ESCC TNM stages and normal tissues to the tumor to elucidate the aberrant metabolic pathways and to provide insights into ESCC progression.

2018年5月1日 · The eighth edition of the American Joint Committee on Cancer Tumor-Node-Metastasis (AJCC TNM) staging system for cancer of the esophagus and esophagogastric junction is based on the Worldwide Esophageal Cancer Collaboration (WECC) database, which includes information on 22,654 patients from 33 institutions in six continents 2, 3, 4.

2025年1月20日 · Patients suffer from esophageal squamous cell carcinoma (ESCC), which is the ninth highly aggressive malignancy. Tumor-infiltrating immune cells (TIIC) exert as major component of the tumor microenvironment (TME), showing possible prognostic value in ESCC.

The present study aims to compare the 7th and the proposed 8th edition of the AJCC/UICC TNM staging system for esophageal squamous cell carcinoma (ESCC). Methods: A total of 1872 ESCC patients who underwent radical surgery with curative intent were analyzed retrospectively.

2022年3月14日 · We aim to elucidate dominantly metabolic pathway in all ESCC tumor/node/metastasis (TNM) stages and adjacent cancerous tissues. We collected 60 postoperative esophageal tissues and 15 normal tissues adjacent to the tumor, then performed Liquid Chromatography with tandem mass spectrometry (LC-MS/MS) analyses.

2025年3月17日 · Background Metabolite-protein interactions (MPIs) are crucial regulators of cancer metabolism; however, their roles and coordination within the esophageal squamous cell carcinoma (ESCC) microenvironment remain largely unexplored. This study is the first to comprehensively map the metabolic landscape of the ESCC microenvironment by integrating an MPI network with multi-scale transcriptomics ...

2022年6月1日 · The study results suggest that the novel models integrating tumor length and tumor thickness may provide a simple and widely available method for evaluating the prognosis of non-operative ESCC patients. The tumor length and tumor thickness should be considered as prognostic factors for ESCC.