2021年9月6日 · Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we...

2020年12月8日 · Here, we obtain a detailed immune cell atlas of esophageal squamous cell carcinoma (ESCC) at single-cell resolution. Exhausted T and NK cells, regulatory T cells …

2025年2月1日 · This review summarizes the latest literature on single-cell research in the field of ESCC, aiming to elucidate the heterogeneity of tumor cells, immune cells, and stromal cells at …

2025年1月1日 · In this study involving 12 metastatic ESCC patients, we employed single-cell sequencing, spatial transcriptomics (ST), and multiplex immunohistochemistry (mIHC) to …

Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignancies with complex tumor microenvironment (TME) which has been proven to be associated with …

本研究对60个 ESCC 患者和4例正常组织的208659个单细胞转录组数据进行分析，揭示了 ESCC 的 TME 组成。 阐明了肿瘤细胞和 TME 细胞之间可能的相互作用以及 TME 中不同细胞类型 …

单细胞转录组分析提供了一种方式，用于全方面研究这些肿瘤微环境（TME）中的免疫细胞。 本研究纳入7例病理诊断为ESCC的患者进行单细胞RNA-seq分析，手术切除后立即获得配对的、 …

食管鳞状细胞癌 (ESCC)是世界上常见的恶性肿瘤，其发展由正常上皮细胞转变为上皮内瘤变，最后转变为浸润性癌。 食管上皮内瘤变根据上皮层置换非典型鳞状细胞的厚度可分为低级别上 …

2024年4月2日 · The efficacy of neoadjuvant chemo-immunotherapy (NAT) in esophageal squamous cell carcinoma (ESCC) is challenged by the intricate interplay within the tumor …

2025年3月17日 · Background Metabolite-protein interactions (MPIs) are crucial regulators of cancer metabolism; however, their roles and coordination within the esophageal squamous …