Spontaneous bacterial peritonitis (SBP) is a severe complication of liver cirrhosis whose diagnosis is based on a polymorphonuclear leukocyte (PMN) value >250 mm 3, yet this PMN value cannot identify all existing types. The aim of our study was to determine the clinical and biological factors that were associated with SBP and predict its ...

Spontaneous bacterial peritonitis (SBP) is a complication of liver cirrhosis with an increased in-hospital mortality rate. For this reason, the aim of the present study was to examine the main predictors of mortality in order to be able to identify high-risk patients in time and to guide the optimal treatment for prognosis improvement.

2021年5月7日 · Univariate analysis revealed that clinical factors (fever, chills, and hepatic encephalopathy), biological factors such as serum and ascites leukocyte value, polymorphonuclear percentage (PMN), erythrocyte sedimentation rate (ESR) value, previous SBP episodes, and the presence of complications such as acute kidney injury (AKI), sepsis, and ...

2023年12月12日 · Using genetic, imaging, microfluidic, and in vivo approaches, we demonstrated that the mechanosensor Piezo1 in PMN plasmalemma induced spike-like Ca 2+ signals during trans -endothelial migration. Mechanosensing increased …

2016年5月9日 · Matsuda et al showed that cytokine-modulated inhibition of PMN apoptosis at a local site augments PMN functions and induces excessive inflammatory response. The anti-apoptotic B cell lymphoma-2 (Bcl-2) family members Bcl-X-linked, A1 and myeloid cell leukemia-1, have been demonstrated to inhibit PMN apoptosis and promote survival by ...

It has been observed that polymorphonuclear neutrophils (PMN) increase in number and function during obstructive jaundice (OJ). However, the precise mechanisms underlying PMN apoptosis during OJ remain poorly understood. The aim of the present study was to investigate the modulation of cytochrome …

2016年8月12日 · Polymorphonuclear neutrophils (PMNs) have a major role in the innate immune system. However, little is known about PMN contribution in relation to oral health. The...

2009年7月8日 · The polymorphonuclear (PMN) elastase is secreted by activated granulocytes and is widely used as a marker of male accessory gland infection.

To simplify the nomenclature in this review, we use the term neutrophils for classically activated antitumor neutrophils; PMN-MDSC for pathologically activated, pro-tumorigenic immunosuppressive neutrophils; and PMN-MDSC TME for …

Morphological changes of mitochondrial PMN. Left panel, morphological changes of the PMN as determined by TEM (magnification, ×8,000). Fewer apoptotic PMN and more normal PMN were observed at 72 h in the BDL group, but differing results were found in the control group and sham and BDL + Cytc groups at the corresponding time points, which ...