Excitatory amino acid transporter 3 is a member of the high-affinity glutamate transporters which plays an essential role in transporting glutamate across plasma membranes in neurons.

EAAT3 internalization results in potentiation of glutamate receptor responses in midbrain dopamine neurons primarily due to activation of NMDA receptors containing NR2B subunits …

The neuronal excitatory amino acid transporter 3 (EAAT3) is fairly ubiquitously expressed in the brain, though it does not necessarily maintain the same function everywhere. It is important in …

2021年3月3日 · Human excitatory amino acid transporter 3 (hEAAT3) mediates glutamate uptake in neurons, intestine, and kidney. Here, we report cryo-EM structures of hEAAT3 in several …

EAAT3/EAAC1 establishes a physical and functional interaction with NCX1, making up a macromolecular complex able to modulate the glutamatergic machinery towards energy …

2016年6月21日 · Excitatory amino acid transporter 3 (EAAT3, encoded by SLC1A1) is an epithelial type high-affinity anionic amino acid transporter, and glutamate is the major oxidative …

2019年2月1日 · EAAT3 internalization results in potentiation of glutamate receptor responses in midbrain dopamine neurons primarily due to activation of NMDA receptors containing NR2B …

2014年10月2日 · Excitatory amino acid transporters (EAATs) limit glutamatergic signaling and maintain extracellular glutamate concentrations below neurotoxic levels. Of the five known …

2012年4月4日 · Clearance of glutamate is catalyzed by glutamate transporters, of which the glutamate/aspartate transporter (GLAST, also known as EAAT1) and glutamate transporter-1 …

Excitatory Amino Acid Transporter 3 (EAAT3) is a neuronal transporter that primarily facilitates the uptake of cysteine into neurons, contributing to neuronal glutathione synthesis. You might find …