Epstein Barr virus (EBV) nuclear antigen 2 (EBNA2) is an EBV-encoded nuclear protein of 82 kD. EBNA2 is necessary for transformation of EBV-infected B lymphocytes and has been shown to …

One of the first viral genes expressed after infection, the Epstein-Barr virus nuclear antigen-2 (EBNA-2) plays an important role in B cell transformation. EBNA-2 initiates and maintains proliferation of transformed cells and prevents apoptosis of the transformed B cells.

The Epstein–Barr virus nuclear antigen 2 (EBNA-2) is one of the six EBV viral nuclear proteins expressed in latently infected B lymphocytes is a transactivator protein. EBNA2 is involved in the regulation of latent viral transcription and contributes to the immortalization of EBV infected cells.

Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues. For the initial technical component only immunohistochemical (IHC) stain performed, the …

2023年12月4日 · EBNA2 subverts Notch signaling (21) and transcriptionally activates a cascade of primary and secondary target genes, most prominently the cellular proto-oncogene MYC and its targets, and the viral promoters that control LMP1 and LMP2 expression (22).

2015年5月29日 · EBNA-2 is a transcriptional activator that is recruited to DNA by cellular adaptor proteins, carries two transactivation domains, and has the capacity to form dimers or multimers. This study provides the first three-dimensional structure of the EBNA-2 …

Visit the supplier page for more antibody information, including target specificity, validation data, datasheets, and any potential cross-reactivities. Your search returned 42 EBNA2 Antibodies …

Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven B-cell growth transformation process. By activating an array of viral and cellular target genes, EBNA-2 initiates a cascade of events which ultimately cause cell cycle entry and the proliferation of …

2021年8月16日 · Epstein-Barr virus nuclear antigen 2 (EBNA2) is a transactivator of viral and cellular gene expression, which plays a critical role in the Epstein-Barr...