
Sensing Evoked Compound Action Potentials from the Spinal …
Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the ...
A Clinical Feasibility Study of Spinal Evoked Compound Action …
2022年1月1日 · Spinal cord stimulation (SCS) is a treatment for chronic neuropathic pain. Recently, SCS has been enhanced further with evoked compound action potential (ECAP) sensing. Characteristics of the ECAP, if appropriately isolated from concurrent stimulation artifact (SA), may be used to control, and aid in the programming of, SCS systems.
First Report on Real-World Outcomes with Evoked Compound …
A novel closed-loop spinal cord stimulation (SCS) system has recently been approved for use which records evoked compound action potentials (ECAPs) from the spinal cord and utilizes these recordings to automatically adjust the stimulation strength in real time.
A New Direction for Closed-Loop Spinal Cord Stimulation: …
In this report, we provide perspective on a new direction for spinal cord stimulation that unites the latest therapeutic paradigms with one of the newer SCS technologies available—CL control using the spinal evoked compound action potential (ECAP) as a feedback control variable.
Evoked compound action potential (ECAP)-controlled closed-loop …
2024年1月10日 · The evoked compound action potential (ECAP) represents a measure of dorsal column fiber activation. This measure approximates the onset of SCS-induced sensations in humans and provides effective analgesia when used …
ECAP-Controlled Closed-Loop Spinal Cord Stimulation Efficacy ... - PubMed
Here, we present the final 24-month results of the Avalon study, which investigated the use of the first closed-loop SCS system in patients with chronic pain. The system measures the evoked compound action potentials (ECAPs) elicited by each stimulus pulse and drives a feedback loop to maintain the ECAP amplitude near constant.
Evaluating the Evoke ECAP-controlled CL-SCS System | JPR
2023年7月21日 · Recent studies demonstrated the long-term safety and efficacy of ECAP-controlled CL-SCS. Here, we report the design of a prospective, multicenter, single-arm feasibility study to characterize clinical outcomes in a real-world chronic pain population utilizing ECAP-controlled CL-SCS.
Frontiers | The Electrically Evoked Compound Action Potential: …
2017年6月22日 · In the past two decades, the eCAP has been widely recorded in both animals and clinical patient populations using different testing paradigms. This paper provides an overview of recording methodologies and response characteristics of the eCAP, as well as its potential applications in research and clinical situations.
ECAP‐Controlled Closed‐Loop Spinal Cord Stimulation Efficacy …
2021年5月2日 · This system uses the measured ECAP (ie, the patient’s neural response to electrical stimulation), in a feedback mechanism to provide consistent spinal cord activation. The feedback mechanism adjusts stimulation current continuously, millions of times per day and automatically to maintain a target ECAP amplitude during physiological changes ...
Sensing Evoked Compound Action Potentials from the Spinal Cord ... - PubMed
2020年12月4日 · Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant parameters that govern the integrity and morphology of acquired ECAPs, and the implications for pain management ...