2024年12月24日 · ECHDC3 (Enoyl-CoA Hydratase Domain Containing 3) is a Protein Coding gene. Diseases associated with ECHDC3 include Alzheimer Disease 10 and Meningioma, Familial. Among its related pathways is Fatty acid biosynthesis. An important paralog of …

2022年9月12日 · Bioinformatic analysis suggested that ECHDC3 alters the bone marrow microenvironment by inducing NK, resting mast cell, and monocyte differentiation. Knocking down ECHDC3 in AML cells by RNAi promoted the death of …

关于 echdc3 This gene has 5 transcripts (splice variants), 202 orthologues and 13 paralogues. Broad expression in fat (RPKM 46.4), kidney (RPKM 40.8) and 17 other tissues.

2024年2月6日 · ECHDC3 is a risk gene for white matter (WM) hyperintensity and is associated with insulin resistance. This study aimed to investigate whether ECHDC3 variants selectively regulate brain WM microstructures and episodic memory in …

2024年3月5日 · Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans. The relationship of the oleic acid level and ECHDC3 mRNA expression with the extent of coronary lesion.

2025年2月8日 · ECHDC3 Variant Regulates the Right Hippocampal Microstructural Integrity and Verbal Memory in Type 2 Diabetes Mellitus. Genetically (cis-) regulated expression of adipose tissue enoyl-CoA hydratase domain-containing 3 (ECHDC3) and genetic silencing studies in a human adipocyte model suggest that ECHDC3 may play an important role in determining ...

2022年9月11日 · Enoyl-CoA hydratase domain containing 3 (ECHDC3), broadly expressed in adipocytes, is predicted to be active in the mitochondrion, involving fatty acid biosynthesis and lipid metabolism (7).

2019年4月22日 · Enoyl-CoA hydratase domain-containing 3 (ECHDC3) was the top-ranked Matsuda index–correlated cis-eGene. Expression levels of ECHDC3 were positively correlated with Matsuda index, and regulated by cis-eQTL, rs34844369 being the top cis-eSNP in AAGMEx.

Know comprehensive ECHDC3 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.

ECHDC3 是白质 (WM) 高信号的风险基因，与胰岛素抵抗相关。 本研究旨在探讨 ECHDC3 变异是否选择性调节 2 型糖尿病 (T2DM) 患者的大脑 WM 微结构和情景记忆。 我们招募了 106 名 T2DM 患者和 111 名健康对照者。 采用体素一般线性模型探讨 ECHDC3 rs11257311 多态性与 T2DM 诊断对分数各向异性 (FA) 的交互作用。 进行线性调制中介分析以检查 FA 值以 ECHDC3 依赖性方式介导 T2DM 对情景记忆影响的潜力。 我们在右下颞 WM、右内囊前肢、右额叶 WM 和右海马 …