Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues. This can be a symptom of hyperphosphatemia. Formation of osseous tissue in soft tissues such as the lungs, eyes, arteries, or other organs is known as ectopic calcification, dystrophic calcification, or ectopic ossification. [1]

2023年5月26日 · Ectopic calcification, or ectopic mineralization, is a pathologic condition in which calcifications develop in soft tissues . The spectrum of ectopic calcification disorders is broad, ranging from common vascular calcification associated with cardiovascular disease to rare hereditary calcification disorders affecting skin, eyes, brain ...

Ectopic calcification, or ectopic mineralization, is a pathologic condition in which calcifications develop in soft tissues [1]. The spectrum of ectopic calcification disorders is broad, ranging from common vascular calcification associated with cardiovascular disease

2025年1月24日 · Ectopic calcifications occur in tendons, ligaments, entheses, muscles, and fasciae, and are often associated with pain and inflammation. In clinical settings, these calcifications are commonly treated by physical therapy and/or surgical interventions.

2015年10月13日 · In the intima, calcification occurs in two distinct patterns: (I) punctate foci of calcification, which may also undergo osseous metaplasia, including marrow and bone; (II) diffuse calcification, with an undefined biological role of this pattern.

2021年10月24日 · Extracellular matrix mineralization is an essential physiologic process in the skeleto-dental tissues. On the other hand, “soft” tissue mineralization (ectopic calcification), associated with several genetic and chronic metabolic …

1999年3月1日 · Ectopic calcification is defined as inappropriate biomineralization occurring in soft tissues. 1 Ectopic calcifications are typically composed of calcium phosphate salts, including hydroxyapatite, but can also consist of calcium oxalates and octacalcium phosphate as seen in kidney stones. 2 In uremic patients, a systemic mineral imbalance is ...

2023年5月1日 · Exploring the underlying mechanisms of ectopic calcification, followed by screening and identifying therapeutic drugs based on associated signal pathways and molecular targets, is an applicable research model for identifying potential …

Ectopic calcification is a term used to refer to mineralization of soft tissues outside the skeleton. Ectopic calcification commonly occurs in many highly prevalent diseases such as diabetes, chronic kidney disease, and atherosclerotic heart disease.

2016年6月19日 · Calcification of soft tissues is classified as metastatic (disturbance of calcium or phosphorus metabolism leading to ectopic calcification in primarily normal tissue), calcinosis (deposition of calcium in soft tissues in the presence of normal calcium metabolism), or dystrophic (calcium deposition in damaged tissues without generalized ...