Efalizumab (brand name Raptiva, Genentech, Merck Serono) is a formerly available medication designed to treat autoimmune diseases, originally marketed to treat psoriasis. As implied by …

依法利珠单抗 （Efalizumab，藥品商品名為 Raptiva，瑞體膚， 默克）是 牛皮癬 的治療用藥，是一種抗 CD11a 的單株抗體製劑，其作用機制是辨識白血球上的CD11a抗原，使白血球與其他 …

2005年6月13日 · Efalizumab is a monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis. Humanized IgG1 kappa isotype monoclonal antibody that binds to …

Efalizumab is a recombinant, humanized, monoclonal IgG1 antibody designed to down-regulate inflammatory processes in the body (Fig. 1). Administered once weekly by subcutaneous …

2004年6月1日 · Efalizumab (Raptiva; Genentech/Xoma/Serono) is a monoclonal antibody that binds to CD11a, a cell-surface protein that has a key role in the pathological immune response …

克隆人源化抗体Efalizumab并转染中国仓鼠卵巢 (CHO)悬浮细胞后，获得了所需的抗体用于偶联，即抗-CD11a IgGX。 这通过SDS-PAGE分析和电喷雾电离质谱法分别进行了纯化和质量分析。

2024年10月29日 · Raptiva is a man-made form of a protein similar to human antibodies. Efalizumab is made to target and destroy only certain cells in the body. This may help to …

Efalizumab is a humanized recombinant monoclonal IgG1 antibody. It targets multiple stages in the immunopathogenesis of psoriasis: initial T-cell activation, migration of T-cells into dermal …

Efalizumab is a novel immunomodulator that blocks T-cell migration and activation. The drug was initially approved in October 2003 for the treatment of adult patients with chronic moderate to …

Efalizumab is a humanized monoclonal antibody that binds to CD11a, the alpha-subunit of lymphocyte function-associated antigen-1, and consequently inhibits T-cell activation. In …