EFR3A: a new raft domain organizing protein? - PubMed
2023年10月25日 · Results: EFR3A was identified as a candidate protein that interacts with flotillin-2. Moreover, this newly discovered interaction was demonstrated via overlay assay using …
EFR3A Gene - GeneCards | EFR3A Protein | EFR3A Antibody
2024年12月24日 · EFR3A (EFR3 Homolog A) is a Protein Coding gene. Diseases associated with EFR3A include Developmental Malformations-Deafness-Dystonia Syndrome and Autism …
EFR3A: a new raft domain organizing protein? - PMC - PubMed …
A Effect of EFR3A gene silencing on activation of EGF-induced EGF receptor and phospholipase PLCγ1 in HeLa cells via western blotting analysis. B Effect of MβCD on EGFR and PLCγ1 …
EFR3A: a new raft domain organizing protein? | Cellular
2023年10月25日 · EFR3A was identified as a candidate protein that interacts with flotillin-2. Moreover, this newly discovered interaction was demonstrated via overlay assay using …
A gain-of-function variation in PLCG1 causes a new immune
The PLCG1 activating variant resulted in enhanced NF-κB and type II interferon pathways in T cells, and hyperactivated NF-κB and type I interferon pathways in monocytes. Treatment with …
Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling …
2021年9月9日 · Disrupting EFR3A or PI4KA reduces phosphatidylinositol-4-phosphate, phosphatidylserine, and KRAS levels at the plasma membrane, as well as oncogenic signaling …
Molecular basis for plasma membrane recruitment of PI4KA by …
2024年12月20日 · The EFR3A C terminus undergoes a disorder-order transition upon binding to the PI4KA complex, with an unexpected direct interaction with both TTC7B and FAM126A. …
EFR3A being a putative otillin-2 partner was conrmed via western blotting (WB) with anti-EFR3 antibodies, co-immunoprecipitation (Co-IP) on HeLa cells, and overlay assay on puried …
EFR3s are palmitoylated plasma membrane proteins that …
2015年1月1日 · Here, we find that Efr3s plays a role in maintaining responsiveness to the type-I angiotensin II (AngII) receptors. siRNA-mediated depletion of EFR3A and EFR3B impaired the …
EFR3A: a new raft domain organizing protein? - ResearchGate
2022年11月20日 · Results: Thereby EFR3A was identified as a candidate protein that interacts with flotillin-2. Moreover, this newly discovered interaction was demonstrated via overlay assay …