2024年12月24日 · EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F) is a Protein Coding gene. Diseases associated with EIF3F include Intellectual Developmental Disorder, Autosomal …

2021年3月18日 · An identical homozygous missense variant in EIF3F, identified through a large-scale genome-wide sequencing approach, was reported as causative in nine individuals with a …

Part of eukaryotic translation initiation factor 3 complex. Implicated in autosomal recessive non-syndromic intellectual disability. [provided by Alliance of Genome Resources, Apr 2022]

eIF3f mediates restriction of HIV-1 expression through a set of factors that includes eIF3f, the SR protein 9G8, and the cyclin-dependent kinase 11 (CDK11). eIF3f may inhibit translation by …

2023年8月11日 · 导读： eIF3f，以前称为翻译起始因子eIF3的亚基之一，是一种不仅在翻译起始中起作用，而且在基因调控和疾病中起作用的蛋白质。 它实际上与泛素介导的蛋白质降解机制 …

eIF3（eukaryotic initiation factor 3，真核起始因子3）是最大的真核起始因子，在哺乳动物细胞中，其分子量超过了600KDa。 eIF3是真核翻译起始进程中起着核心作用。 例如，eIF3可以 …

2006年3月15日 · 我们首次证明，使用癌症谱分析芯片可在大多数人类肿瘤中下调eIF3f的表达，并通过实时逆转录PCR在黑色素瘤和胰腺癌中得到证实。 eIF3f的过表达抑制黑素瘤和胰腺癌细 …

2021年3月18日 · Background: An identical homozygous missense variant in EIF3F, identified through a large-scale genome-wide sequencing approach, was reported as causative in nine …

2024年8月4日 · Enables deubiquitinase activity and identical protein binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; …

In this manuscript, we discuss the interactome and function of each subunit of the human eIF3 complex. Furthermore, we review how altered levels of eIF3 subunits correlate with …