2024年12月24日 · EIF4A3 (Eukaryotic Translation Initiation Factor 4A3) is a Protein Coding gene. Diseases associated with EIF4A3 include Robin Sequence With Cleft Mandible And Limb …

Eukaryotic initiation factor 4A-III is a protein that in humans is encoded by the EIF4A3 gene. [5][6][7] This gene encodes a member of the DEAD box protein family. DEAD box proteins, …

2021年8月16日 · 进一步研究证明，eif4a3缺失通过irbc介导的p53诱导和细胞周期调节因子转录的重编程诱导细胞周期阻滞。 EIF4A3基因敲除能通过多种机制诱导细胞死亡。

EIF4A3 (eukaryotic translation initiation factor 4A3) is an RNA helicase and core component of the exon junction complex. While this RNA-binding protein (RBP) is well-characterized for its …

2021年8月9日 · 本文研究的主要结论表明， 剔除或抑制eIF4A3就能激活p53，从而通过干扰核糖体的生物合成来改变蛋白质的制造过程，进而抑制癌细胞的生长。 了解eIF4A3蛋白的重要性或 …

该论文从RNA解旋酶两大家族Ddx/Dhx基因中筛选并发现了eIF4A3（又名Ddx48）调控胚胎干细胞的稳态维持，并深入阐明了eIF4A3介导的转录后调控特异性细胞周期基因以维持胚胎干细胞 …

EIF4A3 is a gene involved in RNA metabolism, plays a role in mandible, laryngeal, and limb morphogenesis. Richieri-Costa-Pereira syndrome is caused by mutations in EIF4A3. The …

2022年11月23日 · Eukaryotic initiation factor 4A-III (eIF4A3) has been shown to promote influenza A virus (IAV) replication by promoting viral mRNA splicing and spliced mRNA nuclear …

2021年6月22日 · Among the top regulators, we identified the eukaryotic translation initiation factor 4A-3 (eIF4A3). Here we show that depletion of eIF4A3 leads to a potent increase in …

以保守基序 Asp-Glu-Ala-Asp (DEAD) 为特征的 DEAD 盒蛋白是推定的 RNA 解旋酶。 它们涉及许多涉及 RNA 二级结构改变的细胞过程，例如翻译起始、核和线粒体剪接以及核糖体和剪接体 …