Epidemic keratoconjunctivitis (EKC) is an ocular surface infection caused by adenovirus. To date, there are no approved topical antiadenoviral therapeutics to treat EKC. Recent research reveals that treatment with topical corticosteroids for ...

Epidemic keratoconjunctivitis (EKC) is a highly contagious form of viral conjunctivitis. The development of corneal inflammation (keratitis) distinguishes epidemic keratoconjunctivitis from other forms of conjunctivitis and usually arises after …

2017年12月15日 · There were several faint subepithelial infiltrates (SEI) in both corneas and perhaps one or two white blood cells in the anterior chambers. Inspection of the palperbral conjunctiva revealed a pronounced follicular response in each eye. Palpation of her preauricular nodes showed the glands to be swollen and tender bilaterally.

Epidemic keratoconjunctivitis (EKC) is the most severe ocular manifestation of HAdV infection, in which the presence of subepithelial infiltrates (SEIs) in the cornea is a hallmark feature of corneal involvement. SEIs have the tendency to recur and may lead to long-term visual disability.

Epidemic keratoconjunctivitis (EKC) can present with symptoms such as chemosis, eye pain, itching, hyperemia, photophobia and swelling of eyelids that can have a negative effect on everyday life. In approximately 80% of the patients, keratitis with subepithelial infiltrations (SEI) can ensue the conjunctivitis [ 3 , 4 ].

2022年3月3日 · Two recently published narrative reviews concluded that artificial tears, ganciclovir, CsA, and tacrolimus were promising interventions for relieving EKC symptoms, treating SEI, or preventing SEI development (Jonas 2020; Labib 2020). These two reviews also covered studies evaluating non‐steroidal anti‐inflammatory agents (NSAIDs ...

2022年8月1日 · To summarize key findings from a Cochrane systematic review of the effectiveness and safety of topical pharmacologic interventions compared with active control or placebo for epidemic keratoconjunctivitis (EKC). Systematic review.

2025年1月7日 · A highly contagious infection caused by human adenovirus species D (HAdV-D), epidemic keratoconjunctivitis (EKC) results in corneal subepithelial infiltration (SEI) by leukocytes, the hallmark of the infection. To date, the pathogenesis of corneal SEI formation in …

Methods: The patients who developed bilateral SEI following epidemic keratoconjunctivitis (EKC) were applied topical loteprednol on one eye (group 2) and topical dexamethasone on the other (group 1). Results: Decrease in the symptoms was faster in the dexamethasone group, but this difference between the groups was not statistically significant ...

2022年3月3日 · Epidemic keratoconjunctivitis (EKC) is a highly contagious subset of adenoviral conjunctivitis that has been associated with large outbreaks at military installations and at medical facilities. It is accompanied by severe conjunctival inflammation, watery discharge, and light sensitivity, and can lead to chronic complications such as corneal ...