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dHAND and eHAND are basic helix-loop-helix (bHLH) transcription factors expressed during embryogenesis and are required for the proper development of cardiac and extraembryonic tissues.

1999年1月1日 · Targeted mutations of dHAND and eHAND in mice have revealed novel pathways of organogenesis in mesodermal and neural crest derivatives. dHAND mutants exhibit hypoplasia of the right ventricle, branchial arches, and aortic arch arteries.

2024年3月29日 · 为了解决这些局限性，本文提出了一种高效局部注意力（Efficient Local Attention，ELA）方法，通过分析Coordinate Attention (CA) method的局限性，确定了Batch Normalization中泛化能力的缺乏、降维对通道注意力的不利影响以及注意力生成过程的复杂性。

2000年10月10日 · Based on the high degree of amino acid identity between eHAND and dHAND, it is possible that dHAND could also form homodimers and heterodimers with eHAND. We show using yeast and mammalian 2-hybrid as well as biochemical pull-down assays that eHAND and dHAND are capable of forming both HAND homo- and heterodimers in vivo.

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1995年12月22日 · Two bHLH genes, dHAND and eHAND, have now been isolated that are expressed in the bilateral heart primordia and subsequently throughout the primitive tubular heart and its derivatives during chick and mouse embryogenesis.