2025年1月9日 · Serum transferrin saturation. This test measures the amount of iron bound to the protein transferrin that carries iron in the blood. Transferrin saturation values greater than 45% are considered too high.

2020年4月21日 · A high transferrin level in the blood, called hypertransferrinemia, is a sign of iron deficiency (iron-deficiency anemia). The liver tries to increase the production of transferrin to maximize the iron transport and compensate the iron deficiency.

2021年1月15日 · In healthy people, transferrin levels will normally be between 200 – 370 mg/dL (milligrams per deciliter). Levels may vary slightly between laboratories, due to differences in equipment, techniques, and chemicals used. The most common cause of high transferrin levels is iron deficiency [8, 9, 10].

Transferrin saturation >45% in women and >50% in men is generally regarded as elevated [31,36,80]. Upon such levels, iron-loading anemias must also be ruled out through the measurement of hemoglobin, reticulocytes, full blood count, and mean corpuscular volume as a …

2022年12月21日 · Transferrin test — directly measures the protein level in the blood. The level depends upon liver function and your nutritional status. Transferrin, a protein that may decrease during any inflammatory process, is referred to as a negative acute phase reactant.

The normal range for transferrin is 215 to 380 mg/dl. If you have a higher amount, you may have iron-deficiency anemia. If you have a lower level, you may have another problem, such as liver disease or hemolytic anemia.

Transferrin is the main iron transport protein; its synthesis is inversely proportional to body iron stores. Hence, levels increase in iron deficiency to facilitate iron absorption. Transferrin levels are often low in inflammatory anaemia as transferrin expression is negatively affected by cytokines. Ferritin is the main iron storage protein ...

2020年4月23日 · A high percentage of transferrin saturation shows an iron overload in the body. A high percentage of transferrin saturation may be a sign of hemochromatosis , a hereditary disease that is related to iron accumulation in some organs and tissues.

2019年5月3日 · Low transferrin can be due to poor production of transferrin by the liver (where it’s made) or excessive loss of transferrin through the kidneys into the urine. Many conditions including infection and malignancy can depress transferrin levels.

High transferrin is normally seen in iron deficiency anemia, in pregnancy and in treatment with hormone replacement, particularly estrogen. Conditions that can cause low transferrin levels are: Furthermore, trransferrin levels can be low with anemias caused by chronic infectious diseases or inflammation. Was this information helpful?