
005628 - Emx1[IRES cre] , Emx1-Cre Strain Details - The Jackson …
005628 B6.129S2- Emx1 tm1(cre)Krj /J Emx1-IRES-Cre knock-in mice have the endogenous Emx1 locus directing expression of Cre recombinase to approximately 88% of the neurons of …
Emx1-IRES-Cre - 南模生物
将IRES-Cre插入到小鼠Emx1基因终止密码子处。 应用领域 :Cre工具,88%的大脑皮层和海马神经元,大脑皮质神经胶质细胞等区域 *使用本品系发表的文献需注明: Emx1-IRES-Cre mice …
【小鼠大学问】条件性基因敲除的那些坑 - 知乎
比如,受神经元特异性 Emx1(empty spiracles homolog 1)启动子驱动的 Cre 小鼠,除了在新皮质和海马中高表达 Cre 以外,在肾脏和胸腺中也会表达 Cre。 图1. Emx1-Cre在大脑(A)、 …
神经科学Cre工具鼠 - 知乎 - 知乎专栏
Emx1-Cre. 用途:Emx1是大脑皮层和海马体发育中的一个重要转录因子。 应用: • 用于研究大脑皮层和海马体中的基因功能。 • 皮层神经元特异性基因敲除,研究大脑发育和功能。 Gorski, …
Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, …
2002年8月1日 · By homologous recombination of an internal ribosome entry site and Cre recombinase coding region into the 3′-untranslated region of the mouse Emx1 gene, we have …
海马区组织特异性 cre 工具鼠 - 豆丁网
2014年6月19日 · 目前已构建的 EMX1-cre 工具鼠中,Emx1. tm1(cre)Krj. 最常用,可在 Jackson Lab 直接购买。 Emx1. tm1(cre)Krj. 的活性表现在88%的大脑皮层及海马中的神经元细胞, …
Specificity and efficiency of Cre-mediated recombination in Emx1-Cre ...
2000年7月5日 · We reported previously the creation of a line of transgenic mice in which the cre gene was placed directly downstream of the putative Emx1 promoter using ES cell technology. …
Generation of Emx1-Cre mice and their cortex-restricted.
To assess the temporal and spatial speci®city of Cre-mediated recombination in Emx1-Cre mice, we crossed Emx1 Cre/Cre mice with ... ... homeobox gene, Emx1, which is expressed …
Symmetric neural progenitor divisions require chromatin-mediated ...
2020年7月31日 · To distinguish potential Ino80 functions in proliferating NPCs versus postmitotic neurons, we used two complementary Cre lines for Ino80 deletion. Emx1Cre mediates …
Emx1-Cre Is Expressed in Peripheral Autonomic Ganglia That …
The Emx1-IRES-Cre transgenic mouse is commonly used to direct genetic recombination in forebrain excitatory neurons. However, the original study reported that Emx1-Cre is also …