View mouse En1 Chr1:120530246-120535719 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression

2025年3月30日 · EN1 (Engrailed Homeobox 1) is a Protein Coding gene. Diseases associated with EN1 include Endove Syndrome, Limb-Brain Type and Eccrine Porocarcinoma. Among its …

2023年2月6日 · Here we report the identification of the ECE20 enhancer and show it has conserved functionality in mouse and human developing skin ectoderm. Unlike ECE18, knock …

2016年3月3日 · Here we investigated the role of En1 in early mid-hindbrain development, using multiple En1-ablated mouse models as well as lineage-tracing techniques, and observed the …

Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode …

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in …

2021年3月3日 · En1 mutant mice died shortly after birth and exhibited multiple developmental defects. The pattern of defects suggested a cell-autonomous role for En1 in generation and/or …

Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions.

Mice with a heterozygous disruption of the engrailed 1 ( En1) gene En1+/- in an En2 wild-type ( En2+/+) context. Corresponding human genotype: Evidence indicate that polymorphism in the …

2025年2月8日 · EN1 Regulates Cell Growth and Proliferation in Human Glioma Cells via Hedgehog Signaling. Genetic targeting of adult Renshaw cells using a Calbindin 1 destabilized …