Ensembl is a genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation. Ensembl annotate genes, computes multiple alignments, predicts regulatory function and collects disease data.

The Ensembl project produces genome databases for vertebrates and other eukaryotic species, and makes this information freely available online.

Ensembl aims to maintain stable identifiers for genes (ENSG), transcripts (ENST), proteins (ENSP) and exons (ENSE) as long as possible. Changes within the genome sequence assembly or an updated genome annotation may dramatically change a gene model.

More about the Ensembl regulatory annotation. Experimental data sources. Download all regulatory features (GFF).

The Ensembl project seeks to enable genomic science by providing high quality, integrated annotation on chordate and selected eukaryotic genomes within a consistent and accessible infrastructure. All data are open access and all software is open source, i.e. freely available to the scientific community.

What is Ensembl? Ensembl provides a genome browser that acts as a single point of access to annotated genomes for mainly vertebrate species (Video 1 and Figure 2). Information about genes, transcripts and further annotation can be retrieved at the genome, gene and protein level.

Ensembl genome database project is a scientific project at the European Bioinformatics Institute, which provides a centralized resource for geneticists, molecular biologists and other researchers studying the genomes of our own species and other vertebrates and model organisms.

Gene annotation in Ensembl. Gene annotation is the plotting of genes onto genome assemblies, and indexing their genomic coordinates. Gene annotation provided by Ensembl includes automatic annotation, ie genome-wide determination of transcripts.

ensembl-analysis Public Modules to interface with tools used in Ensembl Gene Annotation Process and scripts to run pipelines

The Ensembl project creates evidence-based annotation of genome sequences and integrates these data with other biological information. All of Ensembl's results are freely available to geneticists, molecular biologists, bioinformaticians and the wider research community.