Epsins are a family of highly conserved membrane proteins that are important in creating membrane curvature. Epsins contribute to membrane deformations like endocytosis, and block …

Epsin is a multifaceted protein that apart from its classical role in cargo recognition and endocytic network stabilization, plays a crucial role in signaling. Epsin is required for the activation of the …

Besides inducing membrane curvature, epsin also plays a key function as adaptor protein, coupling various components of the clathrin-assisted uptake and fulfils an important role in …

Epsins are a family of adaptor proteins involved in clathrin-dependent endocytosis. In the vasculature, epsins 1 and 2 are functionally redundant members of this family that are …

1998年8月20日 · Here we investigate the function of Eps15 by characterizing an important binding partner for its region containing EH domains 9; this protein, epsin, is closely related to the …

2002年12月1日 · Endocytic adaptor proteins select specific cargo for internalization by endocytosis through clathrin-coated pits or vesicles. Recent studies indicate that epsins might …

Epsin is a conserved family of endocytic proteins that recognize ubiquitinated membrane receptors, facilitate membrane bending, and aid in the formation of clathrin-coated pits. …

2025年3月25日 · In a porcine carotid artery model, Epsin shRNA coated scaffolds promoted early re endothelialization and reduced IH. These results suggest that Epsin plays a crucial role in …

2018年1月1日 · In fact, epsin is the key player necessary for internalization-mediated activation of the juxtacrine Notch signaling pathway (see below). The epsin family of endocytic adaptors …

2007年1月1日 · Besides inducing membrane curvature, epsin also plays a key function as adaptor protein, coupling various components of the clathrin-assisted uptake and fulfils an important …