Epstein–Barr virus (EBV) is the first identified oncogenic virus, or a virus that can cause cancer. EBV establishes permanent infection in humans. It causes infectious mononucleosis and is also tightly linked to many malignant diseases (cancers). Various vaccine formulations underwent testing in different animals or in humans.

1.1.1 Taxonomy. The Epstein-Barr virus (EBV), the first isolated human tumour virus, was identified in 1964 by Epstein’s group in a cell line derived from Burkitt lymphoma (Epstein et al., 1964). EBV is a human herpesvirus, classified within the gammaherpesviruses subfamily, and is the prototype of the Lymphocryptovirus genus. In keeping with ...

2023年8月8日 · Identify the etiology and epidemiology of Epstein Barr virus. Review the physical exam findings and lab results of patients with Epstein Barr virus. Outline the treatment options and possible complications of Epstein Barr virus.

2019年7月8日 · Initially, EBV was classified into two types: EBV type 1 (EBV-1) and EBV type 2 (EBV-2) (type A and type B), based on alleles at the EBNA2 and EBNA-3A, -3B and -3C genes 14. One of the clinical...

2022年11月29日 · Here, we comprehensively map EPV diversity in 752 published vertebrate genomes, revealing defining aspects of ecology and evolution within individual parvovirus genera. We identify 364 distinct EPV sequences and show these represent approximately 200 unique germline incorporation events, involving at least five distinct parvovirus genera, which ...

Every cell in an LCL carries multiple copies of circular extra-chromosomal viral DNA (episomes) and produces a number of latent proteins, including six nuclear antigens (EBNAs 1, 2, 3A, 3B, 3C and -LP) and three latent membrane proteins (LMPs 1, 2A and 2B) (Fig. 27.1 (b)).

Epstein-Barr virus (EBV) is a gammaherpesvirus and differs in some of its characteristics from the alpha and beta subfamilies of herpesviruses whose members include herpes simplex virus (HSV) and cytomegalovirus (CMV), respectively [1].

Entomopoxvirinae is a subfamily of viruses, in the family Poxviridae. Insects, human, vertebrates, and arthropods serve as natural hosts. The subfamily contains 4 genera. Diseases associated with this subfamily include: impairment of motility and development. [1][2]

EPV phylogeny and taxonomy. Phylogenetic analyses of the 49 poxvirus core genes ( Fig. 3 ) show that the four new genomes are more closely related to AMEV than to any other poxvirus. This confirms that AHEV, CBEV, CREV, and MySEV, isolated from lepidopteran hosts, belong to the genus Betaentomopoxvirus .

2022年1月1日 · Among these, viruses that infect and cause disease to insects are known as Entomopathogenic viruses (EPVs). EPVs are obligate intracellular parasites having either DNA or RNA encapsulated into a protein coat known as capsid to form the virions or nucleocapsids.