Aescin or escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum (the horse chestnut). Aescin is the main active component in horse chestnut, and is responsible for most of its medicinal properties.

Horse chestnut (Aesculus hippocastanum) is a tree. Horse chestnut contains significant amounts of a poison called esculin and can cause death if eaten raw. Horse chestnut also contains a substance...

2019年4月2日 · Extract from the horse chestnut seed is a popular dietary supplement commonly used to improve vein health and reduce inflammation. The main active component in horse chestnut extract is aescin,...

2024年11月22日 · Oral horse chestnut seed extract is effective in the short-term treatment of mild to moderate long-term venous insufficiency, but not for post-thrombotic syndrome. Other investigations focus on the role of the major component aescin in male fertility, antiobesity, and anti-inflammatory effects. Aescin gel has been evaluated for use in bruising.

2024年10月18日 · Escin, also called aescin, is the main saponin (a type of carbohydrate) of Aesculus hippocastanum, or horse chestnut, a tree native to parts of Europe, Asia, the Middle East, and North America. Like most plant extracts, it exhibits antioxidant properties.

2020年11月20日 · Escin is an anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.

2019年3月5日 · Escin, the active component of Aesculus hippocastanum, or horse chestnut, is available as orally absorbable dragées and as a transdermal gel. The anti-inflammatory and anti-edematous effects of escin have been studied over many years in pre-clinical models.

2023年2月7日 · Escin—a plant-derived triterpenoid saponin—is one example of natural products with a broad therapeutic scope. Initially, escin was proven to manifest potent anti-inflammatory and anti-oedematous effects. However, in the last two decades, other novel activities of escin relevant to cancer treatment have been reported.

Abstract: This review discusses historical and recent pharmacological and clinical data on the anti-edematous, anti-inflammatory, and venotonic properties of escin (Reparil®). Escin, the active component of Aesculus hippocastanum, or horse chestnut, is available as orally absorbable dragées and as a transdermal gel.

Definition: Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility. *Escin. *Escin *Plant Extracts Drug Combinations. *Escin *Heparinoids *Nylidrin Drug Combinations.