2024年9月26日 · Drs Samuel Klempner and Haeseong Park discuss emerging biomarkers and novel therapies for esophageal cancer, including new data from ASCO. ... and even in phase 3 trials, it's kind of humbling to ...

2024年10月29日 · Obviously, when you look at survival curves from CheckMate 649, KEYNOTE-811, any of these large phase 3 studies, there's always about 20%-25% of patients who are alive long-term in the 3-, 4-, 5 ...

2025年1月27日 · Cite this: Adding PD-1 Inhibitor to Chemoradiation Boosts Complete Response in Resectable Esophageal Cancer - Medscape - January 27, 2025.

2024年6月26日 · The true esophageal adenocarcinomas, mostly in the United States and in the West, extend and cross the GEJ. ... if you look at just the general population or large phase 3 studies where only 40% ...

2024年6月12日 · Overall, 438 patients with locally advanced, resectable esophageal adenocarcinoma recruited between February 2016 and April 2020 from 25 sites in Germany and randomized to either FLOT (n = 221) or ...

2024年3月14日 · Approval was based on findings from the open-label, phase 3 RATIONALE 302 trial showing a statistically significant and clinically meaningful overall survival benefit with tislelizumab vs ...

2024年8月28日 · Phase III, Randomised Trial of Avelumab Versus Physician's Choice of Chemotherapy as Third-line Treatment of Patients With Advanced Gastric or Gastro-esophageal Junction Cancer: Primary Analysis ...

2025年1月7日 · In the phase 3 trial, 30% of children (n = 16) had a complete response to treatment 28 days after receiving remestemcel-L and 41% (n = 22) had a partial response. ... hepatocellular carcinoma ...

2022年10月18日 · The oral potassium-competitive acid blocker vonoprazan was noninferior and superior to the proton pump inhibitor lansoprazole for erosive esophagitis in a phase 3 trial.

2025年1月22日 · A diagnosis should be based on the presence of esophageal dysfunction symptoms and at least 15 eosinophils per high-power field on esophageal biopsy, particularly after ruling out non-EoE ...