Ethisterone, also known as ethinyltestosterone, pregneninolone, and anhydrohydroxyprogesterone and formerly sold under the brand names Proluton C and Pranone among others, is a progestin medication which was used in the treatment of gynecological disorders but is now no longer available.

炔孕酮，化学名称为17β-羟基-17α-乙炔基-雄甾-4-烯-3-酮，是一种有机化合物，化学式为C21H28O2，是一种孕激素类药，临床用于功能性子宫出血、月经异常、闭经、痛经等。 类似黄似黄体酮，适用于治疗子营出血或月经过多，也可用于防止先兆性。 本品为17β-羟基-17α-乙炔基-雄甾-4-烯-3-酮，按干燥品计算，含C21H28O2应为97.0%～103.0%。 本品为白色或类白色的结晶性粉末，无臭或几乎无臭。 本品在吡啶中略溶，在三氯甲烷中微溶，在水中几乎不溶。 取本 …

Ethisterone is a 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol. It has a role as a progestin and a drug metabolite.

ethisterone的用量、作用機轉、副作用、懷孕及哺乳用藥與藥物交互作用，ethisterone適應症:機能不全性子宮出血、經痛、月經週期異常、黃體機能不全引起不育症。

Ethisterone is a synthetic compound derived from testosterone by adding an ethinyl group, resulting in reduced androgenicity and increased progestational properties and oral activity. AI generated definition based on: Treatment of the Postmenopausal Woman (Third Edition), 2007

Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders.

Ethisterone (pregneninolone, 17α-ethynyltestosterone or 19–norandrostane) is a progestin. It is the 17α- ethynyl analog of testosterone , and was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S ...

中文名:炔孕酮,英文名:ethisterone,CAS:434-03-7,化学式:C21H28O2,分子量:312.45,密度:1.0697 (rough estimate),熔点:263-269 °C (lit.),沸点:392.36°C (rough estimate),闪点:190.2°C,水溶性:soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C), and water (<1 mg/ml at 25°C).,蒸汽压:7.59E ...

Ethisterone是一种孕激素，可以治疗前列腺癌。 在小鼠中，Ethisterone (剂量范围: 40 μg-5 mg/day × 6) 刺激体重增加但硫酸盐的掺入速度有微弱的影响。 Ethisterone 导致标记率快速增加，并且成熟雌性青蛙和青鱼的骨针细胞开始自发出现在关节板的边缘区的中心位置，数量在第五天是对照组的10倍以上 . 白色或乳白色结晶性粉。 熔点269-275℃，在190-195℃高真空中升华。 微溶于乙醇、丙酮、乙醚、氯仿和植物油，实际上不溶于水。 类似黄似黄体酮，适用于治疗子 …